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The 5th congress of the international xenotransplantation association
Presidential address: Why Xenotransplantation? C.G Groth page 833 Full Text | Full-Text PDF (41 KB)
Opening address: Welcome to Nagoya1 Hiroshi Takagi page 835 Full Text | Full-Text PDF (44 KB)
Acute vascular rejection J.L Platt pages 839-840 Full Text | Full-Text PDF (46 KB)
Immunohistological study on the graft following all O- and xenotransplantation in recipients with preformed antibody K Morozumi, T Kobayashi, M Katoh, T Oikawa, Y Ohtsuka, A Itoh, T Usami, O Takeuchi, K Koyama, G Kimura, A Takeda, A Yoshida, T Haba, Y Tomonaga, K Uchida, I Yokoyama, S Hayashi, Y Nagasaka, S Namii, A Nakao, H Takagi pages 841-842 Full Text | Full-Text PDF (53 KB)
Differential expression of α-Gal epitopes on pig and mouse organs M Tanemura, U Galili page 843 Full Text | Full-Text PDF (48 KB)
Anti-Galactose-α(1,3)Galactose antibody production in α1,3-Galactosyltransferase gene knockout mice after xeno- and allotransplantation A.S.-F Chong, L Blinder, L Ma, D Yin, J Shen, J.W Williams, G Byrne, A Schwarz, L.S Diamond, J.E Logan pages 844-845 Full Text | Full-Text PDF (47 KB)
Genes coding for anti-Gal in knock-out mice for the α1,3Galactosyltransferase gene: analysis by hybridomas Z.C Chen, U Galili pages 846-847 Full Text | Full-Text PDF (49 KB)
Ganglioside xenoantigens in pig lymphocytes and aorta S Magnusson, E Hallberg, J.-E Månsson, E Romano, L Rydberg, V Strokan, L Svensson, M.E Breimer pages 848-850 Full Text | Full-Text PDF (115 KB)
Identification of non-αGal xenoantigens on porcine red blood cells A Zhu pages 851-854 Full Text | Full-Text PDF (144 KB)
Effect of various glycosyltransferases on the swine xenoantigen M Koma, S Miyagawa, K Honke, Y Ikeda, S Koyota, A Murase, S Tsuji, S Miyoshi, H Matsuda, R Shirakura, N Taniguchi page 855 Full Text | Full-Text PDF (48 KB)
In vitro and in vivo inhibition of anti-gal secreting cells Y Xu, D Ryan, C Wu, L Kiessling, J Xu, P Morgan, E Vitetta, M.E White-Scharf, A.D Thall page 856 Full Text | Full-Text PDF (45 KB)
Identification of B cells with receptors for α-Gal epitopes (Galα 1-3Galβ1-4GlcNac-R) in xenograft recipients M Tanemura, U Galili pages 857-858 Full Text | Full-Text PDF (127 KB)
Recombinant Galα1,3Gal-substituted mucin/immunoglobulin chimeras: a superior absorber of anti-pig antibodies J Liu, J Holgersson page 859 Full Text | Full-Text PDF (50 KB)
Plasma perfusion by apheresis through a Gal immunoaffinity column successfully depletes anti-Gal antibody: experience with 275 aphereses in baboons A. Watts, A. Foley, M. Awwad, S. Treter, D. Lambrigts, L. Buhler, S. Gojo, M. Basker, G. Oravec, D.H. Sachs, D. Andrews, D.K.C. Cooper page 860 Full Text | Full-Text PDF (46 KB)
Absence of cross-reactivity between xenoantibodies directed against concordant or discordant xenoantigens in rats P Ji, G.L Xia, M Waer page 861 Full Text | Full-Text PDF (44 KB)
A simple and sensitive quantitative method for determining xenoreactive antibody titers in the mouse-to-rat cardiac transplantation model M Haga, H Hirahara, M Tsuchida, T Watanabe, M Takekubo, J Hayashi pages 862-863 Full Text | Full-Text PDF (111 KB)
Prolonged survival of guinea-pig-to-rat heart xenografts following complement depletion and B-cell-directed immunosuppression by malononitrilamide A Meyer zu Vilsendorf, E Nagel, C Link, A Jörns, J Köhl pages 864-865 Full Text | Full-Text PDF (51 KB)
Analysis of antiporcine antibodies in cynomolgus recipients of porcine kidneys on cyclophosphamide-based immunosuppression R Kunz, M Loss, R Schwinzer, S Rensing, J Kaup, J Klempnauer, M Winkler page 866 Full Text | Full-Text PDF (45 KB)
Development of a donor-specific, automated, and cost-effective cytotoxicity assay for human serum on primary porcine cells G Laaf, S Schuster, U Martin, G Steinhoff, A Haverich, A.R Simon pages 867-868 Full Text | Full-Text PDF (328 KB)
Xenoreactivity of fetal and neonatal baboon intracellular antibody against the pig H Xu, S.R Gundry, L.L Bailey pages 869-871 Full Text | Full-Text PDF (56 KB)
Human natural antibodies that recognize nonαGal antigens on porcine red blood cells A Zhu, R Hurst pages 872-873 Full Text | Full-Text PDF (60 KB)
Immunogenicity of Hanganutziu-Deicher antigens in pig-to-human xenotransplantation T Kobayashi, A Suzuki, I Yokoyama, M Abe, S Hayashi, T Nagasaka, Y Namii, T Kato, T Tokoro, D Liu, A Nakao, H Matsuda, K Morozumi, M.E Breimer, L Rydberg, C.G Groth, A Tibell, O Korsgren, H Takagi page 874 Full Text | Full-Text PDF (48 KB)
Xenoantigenacity of Chinese Neijiang pig-related to xenotransplantation Y Li, T Li, H Bu, J Cheng, Y Chen, Z Yang pages 875-876 Full Text | Full-Text PDF (67 KB)
α-Gal and β-Gal are preferentially expressed on porcine cardiac microvascular endothelium2 R.H Chen, A Kadner, R.N Mitchell, D.H Santerre, D.H Adams pages 877-878 Full Text | Full-Text PDF (199 KB)
Comparison of immunoadsorption by GAL-α 1,3- Gal-paa disaccharide columns and by extracorporeal kidney perfusion in the setting of discordant xenogeneic lung transplantation C Schröder, U Martin, A Simon, G Laaff, K Wiebe, O Galanina, A Haverich, B Lapin, G Steinhoff pages 879-881 Full Text | Full-Text PDF (115 KB)
Natural anti-Gal antibodies constitute 0.2% of intravenous immunoglobulin and are equally retained on a synthetic disaccharide column or on an immobilized natural glycoprotein N Barreau, G Blancho, C Boulet, A Martineau, P Vusio, J Liaigre, N Bovin, D Bouhours, J.-F Bouhours pages 882-883 Full Text | Full-Text PDF (78 KB)
Removal of terminal α-Galactosyl residues by endo-β-galactosidase C, a potent endoglycosidase which acts under physiological pH conditions H Ogawa, H Muramatsu, T Nagasaka, N Kurosawa, T Kobayashi, Y Namii, S Hayashi, I Yokoyama, A Nakao, H Takagi, T Muramatsu page 884 Full Text | Full-Text PDF (52 KB)
Human serum induces apoptosis of isolated mouse cardiomyocytes in vitro M Shimada, M Ogiwara, M Kadokura, H Asano, S Kyo, Y Yokote, R Omoto, J Lucien, J.G Coles pages 885-887 Full Text | Full-Text PDF (82 KB)
Neutralization of anti-αGalactosyl antibodies without immunosuppression prevents hyperacute rejection but not acute vascular rejection of pig organs transplanted into baboons R Manez, F Crespo, E Gonzalez, A Centeno, A Juffe, F Arnal, E Cozzi, D.J.G White, R Duthaler, W Kinzy, R Oehrlein, A Katopodis pages 888-889 Full Text | Full-Text PDF (52 KB)
Augmented anti-αGalactosyl antibodies in adult baboons in the setting of intestinal parasitic infections are not associated with higher titers of anti-pig hemolytic antibody E Lopez, A Centeno, F Crespo, A Juffe, P Filgueira, P Veira, R Warner, A Katopodis, R Manez pages 890-891 Full Text | Full-Text PDF (57 KB)
Efficiency of transgenesis using sperm-mediated gene transfer: generation of hDAF transgenic pigs D Lazzereschi, M Forni, F Cappello, M.L Bacci, C Di Stefano, G Marfé, P Giancotti, L Renzi, H.J Wang, M Rossi, G Della Casa, R Pretagostini, G Frati, P Bruzzone, G Stassi, A Stoppacciaro, V Turchi, R Cortesini, P Sinibaldi, L Frati, M Lavitrano pages 892-894 Full Text | Full-Text PDF (59 KB)
hDAF expression in hearts of transgenic pigs obtained by sperm-mediated gene transfer F Cappello, G Stassi, D Lazzereschi, L Renzi, C Di Stefano, G Marfé, P Giancotti, H.J Wang, A Stoppacciaro, M Forni, M.L Bacci, V Turchi, P Sinibaldi, M Rossi, P Bruzzone, R Pretagostini, G Della Casa, R Cortesini, L Frati, M Lavitrano pages 895-896 Full Text | Full-Text PDF (148 KB)
Modulation of fluid-phase complement activation inhibits hyperacute rejection in a porcine-to-human xenograft model A.E. Fiane, V. Videm, J.D. Lambris, O.R. Geiran, J.L. Svennevig, T.E. Mollnes pages 899-900 Full Text | Full-Text PDF (47 KB)
A surface-bound form of human C1 esterase inhibitor on xenografts: the complement regulatory function K Matsunami, S Miyagawa, M Yamada, R Nakai, M Yoshitatsu, R Shirakura pages 901-902 Full Text | Full-Text PDF (60 KB)
Relative roles of hCD46 and hCD55 in the regulation of hyperacute rejection C.A.E Verbakel, F Bonthuis, S.E Eerhart, M van Dixhoorn, F Grosveld, R.L Marquet, J.N.M IJzermans pages 903-904 Full Text | Full-Text PDF (52 KB)
Prevention of hyperacute rejection by phosphatidylinositol-anchored factor I M Yoshitatsu, S Miyagawa, A Murase, K Matsunami, M Yamada, Y Sawa, S Ohtake, H Matsuda, R Shirakura pages 905-906 Full Text | Full-Text PDF (51 KB)
Effect of adenovirus-mediated gene transfer with 5I2 gene in guinea pig–to–rat xenotransplantation S Hayashi, L.D Kaku, Y Namii, T Tokoro, T Kato, T Kobayashi, I Yokoyama, H Okada, A Nakao pages 907-908 Full Text | Full-Text PDF (46 KB)
Adenovirus-mediated gene transfer of double human complement regulating proteins (DAF, CD59) in xenogeneic rat kidney perfusion M Nagahama, M Shiraishi, K Taira, T Ohshiro, Y Muto pages 909-910 Full Text | Full-Text PDF (86 KB)
Effects of the endothelin-1 receptor antagonist TAK-044 on pulmonary injury in discordant xenotransplantation T Watanabe, J Hayasi, A Isogai, S Shimizu, T Takara, T Asakura, H Moriya, S Kubota, S Yamaguchi pages 911-912 Full Text | Full-Text PDF (216 KB)
Successful generation of transgenic pigs for human decay-accelerating factor and human leucocyte antigen DQ C.-F Tu, S.-L Hsieh, J.-M Lee, L.-L Yang, T Sato, K.-H Lee, C.-N Weng, S.J.T Mao, K Tsuji, C.-J Lee pages 913-915 Full Text | Full-Text PDF (155 KB)
Human CD46 rather than CD55 is a key element in protection against complement activation in vitro M.G.A van Dixhoorn, S Dekker, R.W Janssen, C.A.E Verbakel, F Grosveld pages 916-918 Full Text | Full-Text PDF (243 KB)
T cells interacting with the α-Gal epitope: studies in α1,3Galactosyltransferase knock-out mice M Tanemura, U Galili pages 921-923 Full Text | Full-Text PDF (180 KB)
T cell repertoire alterations in allograft and xenograft rejection processes S Brouard, F Sebille, B Vanhove, K Gagne, A.U Neumann, P Douillard, A Moreau, M.C Cuturi, J.P Soulillou pages 924-925 Full Text | Full-Text PDF (48 KB)
Inhibition of human anti-pig T cell response by anti-CD2, anti-CD40L, and CTLA4-Ig: a comparative study Y Xu, D Ryan, C Wu, H Bazin, D Latinne, M.E White-Scharf, A.D Thall page 926 Full Text | Full-Text PDF (43 KB)
Human monocytes bind to two distinct carbohydrate capping structures on porcine endothelium P Kwiatkowski, J.H Artrip, S.F Wang, R.E Michler, S Itescu page 927 Full Text | Full-Text PDF (45 KB)
Human natural killer cells augment B cell responses to porcine xenoantigens R John, P Kwiatkowski, N Edwards, S.F Wang, S Itescu page 928 Full Text | Full-Text PDF (42 KB)
Effect of the remodeling of a glycoantigen on natural killer cell–mediated direct cytotoxicity R Nakai, S Miyagawa, K Matsunami, M Yamada, M Koma, N Taniguchi, R Shirakura pages 929-930 Full Text | Full-Text PDF (60 KB)
Human monocytes bind to ligands on porcine endothelium containing the Gal α (1,3)-Gal antigen P Kwiatkowski, J.H Artrip, R.E Michler, S.F Wang, I.F.C McKenzie, M.S Sandrin, S Itescu page 931 Full Text | Full-Text PDF (46 KB)
Analysis of granzyme B and caspases pathway in xenogeneic cytotoxicity H Nakajima, I Fujiwara, N Mizuta, K Sakaguchi, H Yamagishi pages 932-934 Full Text | Full-Text PDF (215 KB)
Complement- and xenoantibody-independent discordant xenograft rejection in a guinea pig to rat model P Ji, G.L Xia, M Waer page 935 Full Text | Full-Text PDF (48 KB)
Identification, detection, and in vitro characterization of cynomolgus monkey natural killer cells in delayed xenograft rejection of hDAF transgenic porcine renal xenografts D Quan, C Bravery, G Chavez, A Richards, G Cruz, L Copeman, C Atkinson, B Holmes, H Davies, E Cozzi, D White pages 936-937 Full Text | Full-Text PDF (51 KB)
HLA-G inhibits the transendothelial cell migration of human NK cells: a strategy for inhibiting xenograft rejection A Dorling, N Monk, R Lechler page 938 Full Text | Full-Text PDF (43 KB)
Protection against natural killer-mediated swine endothelial cell lysis by HLA-G and HLA-E K Matsunami, S Miyagawa, R Nakai, M Yamada, R Shirakura pages 939-940 Full Text | Full-Text PDF (50 KB)
Bcl-2 expression in pig cells suppresses the apoptosis caused by human perforin/granzymes- or FasL/Fas-mediated cytotoxicity I Fujiwara, H Nakajima, N Mizuta, K Sakaguchi, N Yoshimura, H Yamagishi, T Oka pages 941-942 Full Text | Full-Text PDF (92 KB)
Avoidance of graft versus host disease by proper titration of cell and radiation dose in a mouse to rat xeno-chimera M.M Mohiuddin, X Qian, Y Qin, V.J DiSesa page 943 Full Text | Full-Text PDF (49 KB)
The 5th congress of the international xenotranplantation association
Inhibitory effect of cathepsin B inhibitor CA 074 on mouse anti-rat mixed lymphocyte reaction: novel immunosuppressive strategy for indirect xenoantigen recognition T Tohyama, H Kiyochi, K Narumoto, K Honda, N Kobayashi, M Kanoh, T Saibara, N Katunuma pages 944-945 Full Text | Full-Text PDF (128 KB)
Structural analysis of hyperacute rejection in cardiac xenotransplantation: comparison of two different donor-recipient species combinations K Miyazaki, S Watanabe, T Miyatake, T Watanabe, S Kubota, T Murashita, K Abe, K Yasuda page 946 Full Text | Full-Text PDF (89 KB)
Modification of antigen-presenting cell functions by heparan sulfate Y Kodaira, J.L Platt page 947 Full Text | Full-Text PDF (42 KB)
Cellular adhesion and proliferative responses of neonatal human lymphocytes to pig endothelial cells H Xu, O Fagoaga, S.R Gundry, L.L Bailey pages 948-949 Full Text | Full-Text PDF (55 KB)
Human T-cell receptor variable gene analysis against porcine peripheral lymphocytes N Kawagishi, N Ohkohchi, H Doi, S Satomi pages 950-951 Full Text | Full-Text PDF (50 KB)
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