Original works: New avenues in transplantationCase reportSuccessful Kidney Transplantation in Epstein Syndrome With Antiplatelet Antibodies and Donor-specific Antibodies: A Case Report
Section snippets
Case Report
The patient was a 35-year-old Japanese man with ES. He was misdiagnosed with refractory chronic idiopathic thrombocytopenia purpura from early childhood. Proteinuria, which was found during his elementary school years, had progressed gradually to renal failure, and a renal biopsy performed at the age of 16 years showed pathological findings compatible with focal segmental glomerulosclerosis. Sensorineural hearing impairment was also noted at that time. He started peritoneal dialysis (PD) when
Discussion
ES, also known as MYH9 RD, is a rare disorder characterized by hearing impairment, macrothrombocytopenia, and renal failure, and the English literature contains only a few reports of successful KT in patients with ES.
The main difficulty in the operative management of patients with ES is perioperative bleeding. One report insists that macrothrombocytopenia has little relation to bleeding complications of surgical interventions for MYH9 RD and is not a contraindication for surgery [12]. On the
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