Transplantation Proceedings
Volume 42, Issue 6 , Pages 2009-2010 , July 2010

Simultaneous Pancreas and Kidney Transplantation With Concurrent Allograft Nephrectomy for Recipients With Prior Renal Transplants Lost to BK Virus Nephropathy: Two Case Reports

  • S. Kubal

      Affiliations

    • Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana
    • ,
  • J.A. Powelson

      Affiliations

    • Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana
    • ,
  • T.E. Taber

      Affiliations

    • Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana
    • ,
  • M.L. Goble

      Affiliations

    • Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana
    • ,
  • J.A. Fridell

      Affiliations

    • Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana
    • Corresponding Author InformationAddress reprint requests to: Jonathan A. Fridell, MD, Assosciate Professor of Surgery, Indiana University School of Medicine, 550 N. University Blvd., #4258, Indianapolis, Indiana 46202

References 

  1. Drachenberg CB, Hirsch HH, Ramos E, Papadimitriou JC. Polyomavirus disease in renal transplantation: review of pathological findings and diagnostic methods. Hum Pathol. 2005;36:1245
  2. Hirsch HH, Knowles W, Dickenmann M, et al. Prospective study of polyomavirus type BK replication and nephropathy in renal-transplant recipients. N Engl J Med. 2002;347:488
  3. Randhawa PS, Finkelstein S, Scantlebury V, et al. Human polyoma virus–associated interstitial nephritis in the allograft kidney. Transplantation. 1999;67:103
  4. Ramos E, Drachenberg CB, Papadimitriou JC, et al. Clinical course of polyoma virus nephropathy in 67 renal transplant patients. J Am Soc Nephrol. 2002;13:2145
  5. Buehrig CK, Lager DJ, Stegall MD, et al. Influence of surveillance renal allograft biopsy on diagnosis and prognosis of polyomavirus-associated nephropathy. Kidney Int. 2003;64:665
  6. Poduval RD, Meehan SM, Woodle ES, et al. Successful retransplantation after renal allograft loss to polyoma virus interstitial nephritis. Transplantation. 2002;73:1166
  7. Ramos E, Vincenti F, Lu WX, et al. Retransplantation in patients with graft loss caused by polyoma virus nephropathy. Transplantation. 2004;77:131
  8. Gupta G, Shapiro R, Thai N, Randhawa PS, Vats A. Low incidence of BK virus nephropathy after simultaneous kidney pancreas transplantation. Transplantation. 2006;82:382
  9. Ison MG, Parker M, Stosor V, Kaufman DB. Development of BK nephropathy in recipients of simultaneous pancreas-kidney transplantation. Transplantation. 2009;87:525
  10. Lipshutz GS, Mahanty H, Feng S, et al. BKV in simultaneous pancreas-kidney transplant recipients: a leading cause of renal graft loss in first 2 years post-transplant. Am J Transplant. 2005;5:366
  11. Hirsch HH, Ramos E. Retransplantation after polyomavirus-associated nephropathy: just do it?. Am J Transplant. 2006;6:7
  12. Doucette KE, Pang XL, Jackson K, et al. Prospective monitoring of BK polyomavirus infection early posttransplantation in nonrenal solid organ transplant recipients. Transplantation. 2008;85:1733
  13. Ginevri F, Pastorino N, de Santis R, et al. Retransplantation after kidney graft loss due to polyoma BK virus nephropathy: successful outcome without original allograft nephrectomy. Am J Kidney Dis. 2003;42:821
  14. Womer KL, Meier-Kriesche HU, Patton PR, et al. Preemptive retransplantation for BK virus nephropathy: successful outcome despite active viremia. Am J Transplant. 2006;6:209

PII: S0041-1345(10)00754-2

doi: 10.1016/j.transproceed.2010.05.089

Transplantation Proceedings
Volume 42, Issue 6 , Pages 2009-2010 , July 2010

Article Tools