Transplantation Proceedings
Volume 42, Issue 1 , Pages 54-56 , January 2010

Citrulline Evaluation in Bowel Transplantation

  • P. Ruiz

      Affiliations

    • Department of Surgery, University of Miami School of Medicine, Miami, Florida, USA
    • Department of Pathology, University of Miami School of Medicine, Miami, Florida, USA
    • Corresponding Author InformationAddress reprint requests to Phillip Ruiz, MD, PhD, Department of Surgery, University of Miami School of Medicine, Rosenstiel Medical Sciences Building, Transplant Laboratories, 1600 NW 10th Avenue, #8150, Miami, FL 33136
  • ,
  • P. Tryphonopoulos

      Affiliations

    • Department of Surgery, University of Miami School of Medicine, Miami, Florida, USA
  • ,
  • E. Island

      Affiliations

    • Department of Surgery, University of Miami School of Medicine, Miami, Florida, USA
  • ,
  • G. Selvaggi

      Affiliations

    • Department of Surgery, University of Miami School of Medicine, Miami, Florida, USA
  • ,
  • S. Nishida

      Affiliations

    • Department of Surgery, University of Miami School of Medicine, Miami, Florida, USA
  • ,
  • J. Moon

      Affiliations

    • Department of Surgery, University of Miami School of Medicine, Miami, Florida, USA
  • ,
  • A. Berlanga

      Affiliations

    • Department of Surgery, University of Miami School of Medicine, Miami, Florida, USA
  • ,
  • T. Defranc

      Affiliations

    • Department of Surgery, University of Miami School of Medicine, Miami, Florida, USA
  • ,
  • D. Levi

      Affiliations

    • Department of Surgery, University of Miami School of Medicine, Miami, Florida, USA
  • ,
  • A. Tekin

      Affiliations

    • Department of Surgery, University of Miami School of Medicine, Miami, Florida, USA
  • ,
  • A.G. Tzakis

      Affiliations

    • Department of Surgery, University of Miami School of Medicine, Miami, Florida, USA

References 

  1. Wu G, Knabe DA, Flynn NE. Synthesis of citrulline from glutamine in pig enterocytes. Biochem J. 1994;299:115
  2. Crenn P, Messing B, Cynober L. Citrulline as a biomarker of intestinal failure due to enterocyte mass reduction. Clin Nutrition. 2008;27:328
  3. Curis E, Crenn P, Cynober L. Citrulline and the gut. Curr Opin Clin Nutrition Metabolic Care. 2007;10:620
  4. Goulet O, Sauvat F. Short bowel syndrome and intestinal transplantation in children. Curr Opin Clin Nutrition Metabolic Care. 2006;9:304
  5. David AI, Selvaggi G, Ruiz P, et al. Blood citrulline level is an exclusionary marker for significant acute rejection after intestinal transplantation. Transplantation. 2007;84:1077
  6. Nadalin S, Biglarnia AR, Testa G, et al. Role and significance of plasma citrulline in the early phase after small bowel transplantation in pigs. Transplant Int. 2007;20:425
  7. Pappas PA, Saudubray JM, Tzakis AG, et al. Serum citrulline and rejection in small bowel transplantation: a preliminary report. Transplantation. 2001;72:1212
  8. Pappas PA, Saudubray JM, Tzakis AG, et al. Serum citrulline as a marker of acute cellular rejection for intestinal transplantation. Transplant Proc. 2002;34:915
  9. Yu HC, Tuteja S, Moon JI, et al. Utilization of dried blood spot citrulline level as a noninvasive method for monitoring graft function following intestinal transplantation. Transplantation. 2005;80:1729
  10. Ruiz P, Weppler D, Nishida S, et al. International grading scheme for acute rejection in small bowel transplantation: implementation and experience at the University of Miami. Transplant Proc. 2006;38:1683
  11. Ruiz P, Bagni A, Brown R, et al. Histological criteria for the identification of acute cellular rejection in human small bowel allografts: results of the pathology workshop at the VIII International Small Bowel Transplant Symposium. Transplant Proc. 2004;36:335

PII: S0041-1345(09)01785-0

doi: 10.1016/j.transproceed.2009.12.029

Transplantation Proceedings
Volume 42, Issue 1 , Pages 54-56 , January 2010