Transplantation Proceedings
Volume 42, Issue 1 , Pages 35-38 , January 2010

Daclizumab and Alemtuzumab as Induction Agents in Adult Intestinal and Multivisceral Transplantation: Rejection and Infection Rates in 40 Recipients During the Early Postoperative Period

  • C. Zanfi

      Affiliations

    • Liver and Multiorgan Transplant Unit, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
    • Corresponding Author InformationAddress reprint requests to Chiara Zanfi, MD, Liver and Multiorgan Transplant Unit, PAD 25, Sant'Orsola-Malpighi Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy
    • ,
  • A. Lauro

      Affiliations

    • Liver and Multiorgan Transplant Unit, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
    • ,
  • M. Cescon

      Affiliations

    • Liver and Multiorgan Transplant Unit, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
    • ,
  • A. Dazzi

      Affiliations

    • Liver and Multiorgan Transplant Unit, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
    • ,
  • G. Ercolani

      Affiliations

    • Liver and Multiorgan Transplant Unit, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
    • ,
  • G.L. Grazi

      Affiliations

    • Liver and Multiorgan Transplant Unit, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
    • ,
  • M. Zanello

      Affiliations

    • Liver and Multiorgan Transplant Unit, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
    • ,
  • M. Vivarelli

      Affiliations

    • Liver and Multiorgan Transplant Unit, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
    • ,
  • M. Del Gaudio

      Affiliations

    • Liver and Multiorgan Transplant Unit, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
    • ,
  • M. Ravaioli

      Affiliations

    • Liver and Multiorgan Transplant Unit, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
    • ,
  • A. Cucchetti

      Affiliations

    • Liver and Multiorgan Transplant Unit, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
    • ,
  • G. Vetrone

      Affiliations

    • Liver and Multiorgan Transplant Unit, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
    • ,
  • F. Tuci

      Affiliations

    • Liver and Multiorgan Transplant Unit, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
    • ,
  • P. Di Gioia

      Affiliations

    • Liver and Multiorgan Transplant Unit, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
    • ,
  • T. Lazzarotto

      Affiliations

    • Microbiology Unit, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
    • ,
  • A. D'Errico

      Affiliations

    • Pathology “F. Addarii” Institute, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
    • ,
  • A. Bagni

      Affiliations

    • Pathology “F. Addarii” Institute, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
    • ,
  • S. Faenza

      Affiliations

    • Liver and Multiorgan Transplant Unit, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
    • ,
  • A. Siniscalchi

      Affiliations

    • Liver and Multiorgan Transplant Unit, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
    • ,
  • L. Pironi

      Affiliations

    • Chronic Intestinal Failure Center, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
    • ,
  • A.D. Pinna

      Affiliations

    • Liver and Multiorgan Transplant Unit, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy

References 

  1. Tzakis AG, Kato T, Nishida S, et al. Alemtuzumab (Campath-1H) combined with tacrolimus in intestinal and multivisceral transplantation. Transplantation. 2003;75:1512
  2. Grant D, Abu-Elmagd K, Reyes J, et al. 2003 report of the Intestinal Transplant Registry: a new era has dawned. Ann Surg. 2005;241:607
  3. Abu-Elmagd K, Costa G, Bond GJ, et al. Evolution of the immunosuppressive strategies for the intestinal and multivisceral recipients with special reference to allograft immunity and achievement of partial tolerance. Transplant Int. 2009;22:96
  4. Pinna AD, Weppler D, Nery JR, et al. Induction therapy for clinical intestinal transplantation: comparison of four different regimens. Transplant Proc. 2000;32:1193
  5. Nishida S, Levi MD, Moon JI, et al. Intestinal transplantation with alemtuzumab (Campath-1H): indication for adult patients. Transplant Proc. 2006;38:1747
  6. Garcia M, Weppler D, Mittal N, et al. Camapth-1H immunosuppression therapy reduces incidence and intensity of acute cellular rejection in intestinal and multivisceral transplantation. Transplant Proc. 2004;36:323

PII: S0041-1345(09)01775-8

doi: 10.1016/j.transproceed.2009.12.019

Transplantation Proceedings
Volume 42, Issue 1 , Pages 35-38 , January 2010

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