Transplantation Proceedings
Volume 41, Issue 9 , Pages 3560-3563 , November 2009

Reversal of Graft Steatosis After Liver Transplantation: Prospective Study

  • J. Li, PhD

      Affiliations

    • Department of Anesthesiology and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China
    • ,
  • B. Liu

      Affiliations

    • Division of Liver Transplantation, West China Hospital, Sichuan University, Chengdu, China
    • ,
  • L.-N. Yan, MD, PhD

      Affiliations

    • Division of Liver Transplantation, West China Hospital, Sichuan University, Chengdu, China
    • Corresponding Author InformationAddress reprint requests to Lu-Nan Yan, MD, PhD, Division of Liver Transplantation, West China Hospital, Sichuan University, Chengdu 610041, China
    • ,
  • Y.-X. Zuo

      Affiliations

    • Department of Anesthesiology and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China
    • ,
  • B. Li

      Affiliations

    • Division of Liver Transplantation, West China Hospital, Sichuan University, Chengdu, China
    • ,
  • Y. Zeng

      Affiliations

    • Division of Liver Transplantation, West China Hospital, Sichuan University, Chengdu, China
    • ,
  • S.F. Zhang

      Affiliations

    • Department of Pathology, West China Hospital, Sichuan University, Chengdu, China
    • ,
  • F.-G. Li

      Affiliations

    • Division of Liver Transplantation, West China Hospital, Sichuan University, Chengdu, China

References 

  1. Busuttil RW, Tanaka K. The utility of marginal donors in liver transplantation. Liver Transpl. 2003;9:651
  2. Brandhagen D, Fidler J, Rosen C. Evaluation of the donor liver for living donor liver transplantation. Liver Transpl. 2003;9:S16
  3. Chavin KD, Fiorini RN, Shafizadeh S, et al. Fatty acid synthase blockade protects steatotic livers from warm ischemia reperfusion injury and transplantation. Am J Transplant. 2004;4:1440
  4. Angele MK, Rentsch M, Hartl WH, et al. Effect of graft steatosis on liver function and organ survival after liver transplantation. Am J Surg. 2008;195:214
  5. Marsman WA, Wiesner RH, Rodriguez L, et al. Use of fatty donor liver is associated with diminished early patient and graft survival. Transplantation. 1996;62:1246
  6. Machicao VI, Krishna M, Bonatti H, et al. Hepatitis C recurrence is not associated with allograft steatosis within the first year after liver transplantation. Liver Transpl. 2004;10:599
  7. Yao FY, Ferrell L, Bass NM, et al. Liver transplantation for hepatocellular carcinoma: comparison of the proposed UCSF criteria with the Milan criteria and the Pittsburgh modified TNM criteria. Liver Transpl. 2002;8:765
  8. Cammà C, Bruno S, Di Marco V, et al. Insulin resistance is associated with steatosis in nondiabetic patients with genotype 1 chronic hepatitis C. Hepatology. 2006;43:64
  9. Johnson SR, Alexopoulos S, Curry M, et al. Primary nonfunction (PNF) in the MELD era: an SRTR database analysis. Am J Transplant. 2007;7:1009
  10. Verran D, Kusyk T, Painter D, et al. Clinical experience gained from the use of 120 steatotic donor livers for orthotopic liver transplantation. Liver Transpl. 2003;9:500
  11. Nocito A, El-Badry AM, Clavien PA. When is steatosis too much for transplantation?. J Hepatol. 2006;45:494
  12. McCormack L, Petrowsky H, Jochum W, et al. Use of severely steatotic grafts in liver transplantation: a matched case-control study. Ann Surg. 2007;246:940
  13. Network TOPaT. http://www.optn.orgAccessed May 1, 2006

PII: S0041-1345(09)01412-2

doi: 10.1016/j.transproceed.2009.06.222

Transplantation Proceedings
Volume 41, Issue 9 , Pages 3560-3563 , November 2009

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