Transplantation Proceedings
Volume 41, Issue 9 , Pages 3701-3703 , November 2009

Lack of Association of Polymorphisms 239+34A/C in the SOD1 Gene and 47C/T in the SOD2 Gene With Delayed Graft Function and Acute and Chronic Rejection of Kidney Allografts

  • G. Dutkiewicz

      Affiliations

    • Department of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University, Szczecin, Poland
    • ,
  • L. Domanski

      Affiliations

    • Department of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University, Szczecin, Poland
    • ,
  • A. Binczak-Kuleta

      Affiliations

    • Department of Laboratory Diagnostics and Molecular Medicine, Pomeranian Medical University, Szczecin, Poland
    • ,
  • A. Pawlik

      Affiliations

    • Department of Pharmacokinetics and Therapeutic Drug Monitoring, Pomeranian Medical University, Szczecin, Poland
    • Corresponding Author InformationAddress reprint requests to Andrzej Pawlik, MD, PhD, Department of Pharmacokinetics and Therapeutic Drug Monitoring, Pomeranian Medical University, Powstancow Wlkp. 72, 70-111 Szczecin, Poland
    • ,
  • K. Safranow

      Affiliations

    • Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, Szczecin, Poland
    • ,
  • V. Dziedziejko

      Affiliations

    • Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, Szczecin, Poland
    • ,
  • M. Wisniewska

      Affiliations

    • Department of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University, Szczecin, Poland
    • ,
  • A. Ciechanowicz

      Affiliations

    • Department of Laboratory Diagnostics and Molecular Medicine, Pomeranian Medical University, Szczecin, Poland
    • ,
  • K. Ciechanowski

      Affiliations

    • Department of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University, Szczecin, Poland

References 

  1. Grinyo JM. Role of ischemia-repefusion injury in the development of chronic renal allograft damage. Transplant Proc. 2001;33:3741
  2. Hower R, Minor TH, Scneeberger H, et al. Assessment of oxygen radicals during transplantation: effect of radical scavenger. Transpl Int. 1996;9:479
  3. Zelko IN, Mariani TJ, Folz RJ. Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2) and EC-SOD (SOD3) gene structures, evolution and expression. Free Rad Biol Med. 2002;33:337
  4. Fattman CH, Schaefer LM, Oury TD. Extracellular superoxide dismutase in biology and medicine. Free Rad Biol Med. 2003;35:236
  5. Crapo JD, Oury TD, Rabouille C, et al. Copper, zinc superoxide dismutase is primarily a cytosolic protein in human cells. Proc Natl Acad Sci. 1992;89:10405
  6. Lookene A, Stenlund P, Tibell LAE. Characterization of heparin binding of human extracellular superoxide dismutase. Biochemistry. 2000;39:230
  7. Racusen LC, Solez K, Colvin BB, et al. The Banff 97 working classification of renal allograft pathology. Kidney Int. 1999;55:713
  8. Hayry P, Isoniemi H, Yilmaz S, et al. Chronic allograft rejection. Immunol Rev. 1993;134:33
  9. Ukkola O, Erkkilä PH, Savolainen MJ, et al. Lack of association between polymorphisms of catalase, copper-zinc superoxide dismutase (SOD), extracellular SOD and endothelial nitric oxide synthase genes and macroangiopathy in patients with type 2 diabetes mellitus. J Intern Med. 2001;249:451
  10. Domanski L, Dolegowska B, Safranow K, et al. Early phase of reperfusion of human kidney allograft does not affect an erythrocyte anti-oxidative system. Nephrology (Carlton). 2006;11:467
  11. Domanski L, Dolegowska B, Safranow K, et al. Activity of CuZn-superoxide dismutase, catalase and glutathione peroxidase in erythrocytes in kidney allografts during reperfusion in patients with and without delayed graft function. Clin Transplant. 2006;20:67
  12. Land W, Scheeberger H, Schleibner S, et al. The beneficial effect of human recombinant superoxide dismutase on acute and chronic rejection events in recipients of cadaveric renal transplants. Transplantation. 1994;57:211
  13. Johnson KJ, Weinberg JM. Postischemic renal injury due to oxygen radicals. Curr Opin Nephrol Hypertens. 1993;2:625
  14. Bayati A, Kallskog O, Odlind B, et al. Plasma elimination kinetics and renal handling of copper/zinc superoxide dismutase in the rat. Acta Physiol Scand. 1988;134:65
  15. Yin M, Wheeler MD, Connor HD, et al. Cu/Zn-superoxide dismutase gene attenuates ischemia-reperfusion injury in the rat kidney. J Am Soc Nephrol. 2001;12:2691
  16. Akizuki E, Akaike T, Okamoto S, et al. Role of nitric oxide and superoxide in acute cardiac allograft rejection in rats. Proc Soc Exp Biol Med. 2000;225:151
  17. Shiraishi T, Kuroiwa A, Shirakusa T, et al. Free radical–mediated tissue injury in acute lung allograft rejection and the effect of superoxide dismutase. Ann Thorac Surg. 1997;64:821
  18. Cristol JP, Vela C, Maggi MF, et al. Oxidative stress and lipid abnormalities in renal transplant recipients with or without chronic rejection. Transplantation. 1998;65:1322
  19. Hass MA, Massaro D. Regulation of the synthesis of superoxide dismutases in rat lungs during oxidant and hyperthermic stresses. J Biol Chem. 1988;263:776
  20. Yoo HY, Chang MS, Rho HM. The activation of the rat copper/zinc superoxide dismutase gene by hydrogen peroxide through the hydrogen peroxide–responsive element and by paraquat and heat shock through the same heat shock element. J Biol Chem. 1988;263:776
  21. Inoue N, Ramasamy S, Fukai T, et al. Shear stress modulates expression of Cu/Zn superoxide dismutase in human aortic endothelial cells. Circ Res. 1996;79:32
  22. Dimmeler S, Hermann C, Galle J, et al. Upregulation of superoxide dismutase and nitric oxide synthase mediates the apoptosis-suppressive effects of shear stress on endothelial cells. Arterioscler Thromb Vasc Biol. 1999;19:656
  23. Singh I, Gulati S, Orak JK, et al. Expression of antioxidant enzymes in rat kidney during ischemia-reperfusion injury. Mol Cell Biochem. 1993;125:97
  24. Davies SJ, Reichardt-Pascal SY, Vaughan D, et al. Differential effect of ischemia-reperfusion injury on anti-oxidant enzyme activity in the rat kidney. Exp Nephrol. 1995;3:348

PII: S0041-1345(09)01408-0

doi: 10.1016/j.transproceed.2009.06.221

Transplantation Proceedings
Volume 41, Issue 9 , Pages 3701-3703 , November 2009

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