Transplantation Proceedings
Volume 41, Issue 9 , Pages 3597-3602 , November 2009

Ischemic Postconditioning Modified Renal Oxidative Stress and Lipid Peroxidation Caused By Ischemic Reperfusion Injury in Rats

  • Y. Yun

      Affiliations

    • Faculty of Pharmacy and Yunnan Key Laboratory of Pharmacology for Natural Products, Yunnan University of Traditional Chinese Medicine, Kunming, People's Republic of China
    • Department of Pharmacology, Yunnan University of Traditional Chinese Medicine, Kunming, People's Republic of China
    • ,
  • W.G. Duan

      Affiliations

    • Kunming Medical College and Key Laboratory of Molecular Biology for Sinomedicine, Yunnan University of Traditional Chinese Medicine, Kunming, People's Republic of China
    • ,
  • P. Chen

      Affiliations

    • Faculty of Pharmacy and Yunnan Key Laboratory of Pharmacology for Natural Products, Yunnan University of Traditional Chinese Medicine, Kunming, People's Republic of China
    • ,
  • H.X. Wu

      Affiliations

    • Faculty of Pharmacy and Yunnan Key Laboratory of Pharmacology for Natural Products, Yunnan University of Traditional Chinese Medicine, Kunming, People's Republic of China
    • ,
  • Z.Q. Shen

      Affiliations

    • Faculty of Pharmacy and Yunnan Key Laboratory of Pharmacology for Natural Products, Yunnan University of Traditional Chinese Medicine, Kunming, People's Republic of China
    • ,
  • Z.Y. Qian

      Affiliations

    • Faculty of Pharmacy and Yunnan Key Laboratory of Pharmacology for Natural Products, Yunnan University of Traditional Chinese Medicine, Kunming, People's Republic of China
    • ,
  • D.H. Wang

      Affiliations

    • Faculty of Pharmacy and Yunnan Key Laboratory of Pharmacology for Natural Products, Yunnan University of Traditional Chinese Medicine, Kunming, People's Republic of China
    • Corresponding Author InformationAddress reprint requests to Dian Hua Wang, Faculty of Pharmacy and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical College, 191, Western People's Road, Kunming 650031, People's Republic of China

References 

  1. Sehirli O, Sener E, Cetinel S, et al. Alpha-lipoic acid protects against renal ischaemia-reperfusion injury in rats. Clin Exp Pharmacol Physiol. 2008;35:249
  2. Hernandez DJ, Roberts WB, Miles-Thomas J, et al. Can ischemic preconditioning ameliorate renal ischemia-reperfusion injury in a single-kidney porcine model?. J Endourol. 2008;22:
  3. Timsit MO, Gadet R, Ben Abdennebi H, et al. Renal ischemic preconditioning improves recovery of kidney function and decreases alpha-smooth muscle actin expression in a rat model. J Urol. 2008;180:388
  4. Hausenloy DJ, Yellon DM. Preconditioning and postconditioning: united at reperfusion. Pharmacol Ther. 2007;116:173
  5. Zhao ZQ, Corvera JS, Halkos ME, et al. Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning. Am J Physiol Heart Circ Physiol. 2003;285:H597
  6. Kin H, Zhao ZQ, Sun HY, et al. Postconditioning attenuates myocardial ischemia-reperfusion injury by inhibiting events in the early minutes of reperfusion. Cardiovasc Res. 2004;62:74
  7. Sun HY, Wang NP, Halkos M, et al. Postconditioning attenuates cardiomyocyte apoptosis via inhibition of JNK and p38 mitogen-activated protein kinase signaling pathways. Apoptosis. 2006;11:1583
  8. Szwarc I, Soullier S, Gayrard N, et al. Ischemic postconditioning prevents ischemic acute renal failure. Transplant Proc. 2007;39:2554
  9. Liu X, Chen H, Zhan B, et al. Attenuation of reperfusion injury by renal ischemic postconditioning: the role of NO. Biochem Biophys Res Commun. 2007;359:628
  10. Chen H, Xing B, Liu X, et al. Ischemic postconditioning inhibits apoptosis after renal ischemia/reperfusion injury in rat. Transpl Int. 2008;21:364
  11. Singh D, Kaur R, Chander V, et al. Antioxidants in the prevention of renal disease. J Med Food. 2006;9:443
  12. Yamanobe T, Okada F, Iuchi Y, et al. Deterioration of ischemia/reperfusion-induced acute renal failure in SOD1-deficient mice. Free Radic Res. 2007;41:200
  13. Alaas O, Sahin A, Colak O, et al. Beneficial effects of allopurinol on glutathione levels and glutathione peroxidase activity in rat ischaemic acute renal failure. J Int Med Res. 1996;24:33
  14. Chen CF, Tsai SY, Ma MC, et al. Hypoxic preconditioning enhances renal superoxide dismutase levels in rats. J Physiol. 2003;552:561
  15. Cochrane J, Williams BT, Banerjee A, et al. Ischemic preconditioning attenuates functional, metabolic, and morphologic injury from ischemic acute renal failure in the rat. Ren Fail. 1999;21:135
  16. Jablonski P, Howden BO, Rae DA, et al. An experimental model for assessment of renal recovery from warm ischemia. Transplantation. 1983;35:198
  17. Yan C, Huang A, Wu Z, et al. Increased superoxide leads to decreased flow-induced dilation in resistance arteries of Mn-SOD-deficient mice. Am J Physiol Heart Circ Physiol. 2005;288:H2225
  18. Yun Y, Chen P, Zheng CL, et al. Copper-aspirin complex inhibits cyclooxygenase-2 more selectively than aspirin. Yakugaku Zasshi. 2007;127:1869
  19. Mury CE, Jennings RB, Reimer KA. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation. 1986;74:1124
  20. Ambros JT, Herrero-Fresneda I, Borau OG, et al. Ischemic preconditioning in solid organ transplantation: from experimental to clinics. Transpl Int. 2007;20:219
  21. Zhao H, Sapolsky RM, Steinberg GK. Interrupting reperfusion as a stroke therapy: ischemic postconditioning reduces infarct size after focal ischemia in rats. J Cereb Blood Flow Metab. 2006;26:1114
  22. Sur K, Liu ZS, Sun Q. Role of mitochondria in cell apoptosis during hepatic ischemia-reperfusion injury and protective effect of ischemic postconditioning. World J Gastroenterol. 2004;10:1934
  23. Gathaman KK, Saleem MT, Thanislas PT, et al. Cardioprotective effect of the Hibiscus rosa sinensis flowers in an oxidative stress model of myocardial ischemic reperfusion injury in rat. BMC Complement Altern Med. 2006;6:32
  24. Kin J, Kil IS, Seok YM, et al. Orchiectomy attenuates post-ischemic oxidative stress and ischemia/reperfusion injury in mice (A role for manganese superoxide dismutase). J Biol Chem. 2006;281:20349
  25. Cruhirds DL, Novak L, Akhi KM, et al. Mitochondrial targets of oxidative stress during renal ischemia/reperfusion. Arch Biochem Biophys. 2003;412:27
  26. Fuller BJ, Gower J, Cotterill L, et al. Reperfusion injury and renal metabolism: the temporal relationship between oxidative stress and functional change. Adv Exp Med Biol. 1990;264:389
  27. Sindhu RK, Ehdaie A, Farmand F, et al. Expression of catalase and glutathione peroxidase in renal insufficiency. Biochim Biophys Acta. 2005;1743:86
  28. Annuk M, Zilmer M, Lind L, et al. Oxidative stress and endothelial function in chronic renal failure. J Am Soc Nephrol. 2001;12:2747
  29. Tugtepe H, Sener G, Biyikli NK, et al. The protective effect of oxytocin on renal ischemia/reperfusion injury in rats. Regul Pept. 2007;140:101

 The study was partially supported by a grant from the Department of Graduate, Kunming Medical College of China (11415018).

PII: S0041-1345(09)01357-8

doi: 10.1016/j.transproceed.2009.06.203

Transplantation Proceedings
Volume 41, Issue 9 , Pages 3597-3602 , November 2009

Article Tools

* Image Usage & Resolution