Transplantation Proceedings
Volume 41, Issue 3 , Pages 824-826 , April 2009

Heparin and Hyperbaric Oxygenation in Enteric Autonomic Neuron Preservation for Transplant

  • F.A.G. Guimarães

      Affiliations

    • Departments of Science and Tecnology, Universidade Santa Cecília (UNISANTA), Santos, Brazil
    • ,
  • M.O. Taha

      Affiliations

    • Department of Surgery, Universidade Federal de São Paulo-Escola Paulista de Medicina (UNIFESP-EPM), São Paulo, Brazil
    • Corresponding Author InformationAddress reprint requests to Murched Omar Taha, MD, PhD, Department of Surgery, Federal University of São Paulo, Escola Paulista de Medicina, Rua Botucatu 740, CEP 04023-900, São Paulo, Brazil
    • ,
  • D.J. Fagundes

      Affiliations

    • Department of Surgery, Universidade Federal de São Paulo-Escola Paulista de Medicina (UNIFESP-EPM), São Paulo, Brazil
    • ,
  • R.S. Simões

      Affiliations

    • Department of Histology, Universidade Federal de São Paulo-Escola Paulista de Medicina (UNIFESP-EPM), São Paulo, Brazil
    • ,
  • M.J. Simões

      Affiliations

    • Department of Histology, Universidade Federal de São Paulo-Escola Paulista de Medicina (UNIFESP-EPM), São Paulo, Brazil
    • ,
  • A. Caricati-Neto

      Affiliations

    • Department of Pharmacology, Universidade Federal de São Paulo-Escola Paulista de Medicina (UNIFESP-EPM), São Paulo, Brazil

References 

  1. Wei L, Hata K, Doorschodt BM, et al. Experimental small bowel preservation using Polysol: a new alternative to University of Wisconsin solution, Celsior and histidine-tryptophan-ketoglutarate solution?. World J Gastroenterol. 2007;13:3684
  2. Salehi P, Bigam DL, Ewaschuk JB, et al. Alleviating intestinal ischemia-reperfusion injury in an in vivo large animal model: developing an organ-specific preservation solution. Transplantation. 2008;85:878
  3. Junginger J, Traub F, Ladurner R, et al. Intestinal lipid absorption increases cold ischemia of the small bowel in rats. Transplant Proc. 2008;40:981
  4. Feryha S, Ercan F, Arbak S. Scanning electron microscopic study of cold-stored small bowel: comparison of Euro-Collins and Lactated Ringer's solutions. Dig Dis Sci. 2003;48:1006
  5. Gatti S, Ghidoni P, Rossi G, et al. Enteric nervous system in preservation, reperfusion, and rejection of the pig small bowel. Transplant Proc. 1998;30:2648
  6. Taha MO, Fraga MM, Fagundes DJ, et al. Ascorbic acid prevents autonomic dysfunction in rat jejunal submitted to cold ischemic preservation for transplantation. Transplant Proc. 2004;36:289
  7. Taha MO, Fraga MM, Guimarães FA, et al. Autonomic dysfunction of rat jejunum submitted to cold ischemic preservation is prevented by heparin. Transplant Proc. 2006;38:1779
  8. Guimarães FA, Taha MO, Simoes MJ, et al. Use of hyperbaric oxygenation in small bowel preservation for transplant. Transplant Proc. 2006;38:1796
  9. Monchik GJ, Russel PS. Transplantation of small bowel in the rat: technical and immunological considerations. Surgery. 1971;70:693
  10. Guimarães FAG, Taha MO, Simões MJ, et al. A novel system for organ and tissues preservation: the refrigerating hyperbaric chamber. Transplant Proc. 2006;38:1879
  11. Quaedackers JSLT, Beuk RJ, Bennet L, et al. An evaluation of methods for grading histologic injury following ischemia/reperfusion of the small bowel. Transplant Proc. 2000;32:1307
  12. Chen J, Avci FY, Munõz EM, et al. Enzymatic redesigning of biologically active heparan sulfate. J Biol Chem. 2005;280:42817

 Supported by UNISANTA and Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP), São Paulo, Brazil.

PII: S0041-1345(09)00190-0

doi: 10.1016/j.transproceed.2009.02.052

Transplantation Proceedings
Volume 41, Issue 3 , Pages 824-826 , April 2009

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