Transplantation Proceedings
Volume 41, Issue 1 , Pages 44-48 , January 2009

Detection of Local Metabolic Changes After Progressive and Stepwise Reduction of Renal Blood Flow in Pigs

  • A.K. Keller

      Affiliations

    • Institute of Clinical Medicine, Aarhus University, Aarhus, Denmark
    • Corresponding Author InformationAddress reprint requests to Anna Krarup Keller, Institute of Clinical Medicine, Aarhus University Hospital, Brendstrupgaardsvej 100, DK-8200 Aarhus N, Denmark
  • ,
  • T.M. Jorgensen

      Affiliations

    • Department of Urology, Aarhus University Hospital, Aarhus, Denmark
  • ,
  • L.H. Olsen

      Affiliations

    • Department of Urology, Aarhus University Hospital, Aarhus, Denmark
  • ,
  • L.B. Stolle

      Affiliations

    • Department of Plastic Surgery, Aarhus University Hospital, Aarhus, Denmark

References 

  1. Beyga ZT, Kahan BD. Surgical complications of kidney transplantation. J Nephrol. 1998;11:137
  2. Tarzamni MK, Argani H, Nurifar M, et al. Vascular complication and Doppler ultrasonographic finding after renal transplantation. Transplant Proc. 2007;39:1098
  3. Grenier N, Douws C, Morel D, et al. Detection of vascular complications in renal allografts with color Doppler flow imaging. Radiology. 1991;178:217
  4. Gao J, Ng A, Shih G, et al. Intrarenal color duplex ultrasonography: a window to vascular complications of renal transplants. J Ultrasound Med. 2007;26:1403
  5. Perico N, Cattaneo D, Sayegh MH, et al. Delayed graft function in kidney transplantation. Lancet. 2004;364:1814
  6. Weld KJ, Montiglio C, Bush AC, et al. Real-time analysis of renal interstitial metabolites during induced renal ischemia. J Endourol. 2008;22:571
  7. Keller AK, Jorgensen TM, Olsen LH, et al. Early detection of renal ischemia by in situ microdialysis: an experimental study. J Urol. 2008;179:371
  8. Kusudo K, Ishii K, Rahman M, et al. Blood flow-dependent changes in intrarenal nitric oxide levels during anesthesia with halothane or sevoflurane. Eur J Pharmacol. 2004;498:267
  9. Beldi G, Bosshard A, Hess OM, et al. Transit time flow measurement: experimental validation and comparison of three different systems. Ann Thorac Surg. 2000;70:212
  10. Rawashdeh YF, Horlyck A, Mortensen J, et al. Resistive index: an experimental study of acute complete unilateral ureteral obstruction. Invest Radiol. 2003;38:153
  11. Lonnroth P, Jansson PA, Smith U. A microdialysis method allowing characterization of intercellular water space in humans. Am J Physiol. 1987;253:E228
  12. Dalmose AL, Hvistendahl JJ, Olsen LH, et al. Surgically induced urologic models in swine. J Invest Surg. 2000;13:133
  13. Smith AC, Swindle MM. Preparation of swine for the laboratory. ILAR J. 2006;47:358
  14. Sorensen HB, Kristensen AT, Ravn HB, et al. Local application of FFR-rFVIIa reduces thrombus formation at arterial anastomosis in rats. Microsurgery. 1999;19:369
  15. Hom D, Eiley D, Lumerman JH, et al. Complete renal embolization as an alternative to nephrectomy. J Urol. 1999;161:24
  16. Siskin GP, Dowling K, Virmani R, et al. Pathologic evaluation of a spherical polyvinyl alcohol embolic agent in a porcine renal model. J Vasc Interv Radiol. 2003;14:89
  17. Misra S, Gordon JD, Fu AA, et al. The porcine remnant kidney model of chronic renal insufficiency. J Surg Res. 2006;135:370
  18. Sorensen HB. Free jejunal flaps can be monitored by use of microdialysis. J Reconstr Microsurg. 2008;24:443

 Supported by Beckett-Fonden and The A. P. Møller Foundation for the Advancement of Medical Science.

PII: S0041-1345(08)01607-2

doi: 10.1016/j.transproceed.2008.10.089

Transplantation Proceedings
Volume 41, Issue 1 , Pages 44-48 , January 2009