Transplantation Proceedings
Volume 39, Issue 10 , Pages 2970-2974 , December 2007

Relationship Between Procalcitonin Values and Infection in Brain-Dead Organ Donors

  • O. Rangeard

      Affiliations

    • Pôle d’Anesthésie-Réanimation, Centre Hospitalier Universitaire de Nancy, Nancy, France
    • Corresponding Author InformationAddress reprint requests to Dr Olivier Rangeard, Pôle d’Anesthésie-Réanimation, Hopital Brabois-Adutes, 4 rue du Morvan, Vandoeuvre-les-Nancy 54500, France.
    • ,
  • G. Audibert

      Affiliations

    • Pôle d’Anesthésie-Réanimation, Centre Hospitalier Universitaire de Nancy, Nancy, France
    • ,
  • J.-F. Perrier

      Affiliations

    • Pôle d’Anesthésie-Réanimation, Centre Hospitalier Universitaire de Nancy, Nancy, France
    • ,
  • C. Loos-Ayav

      Affiliations

    • Service d’Epidémiologie et d’Evaluation Cliniques, Centre Hospitalier Universitaire de Nancy, Nancy, France.
    • ,
  • J.-M. Lalot

      Affiliations

    • Pôle d’Anesthésie-Réanimation, Centre Hospitalier Universitaire de Nancy, Nancy, France
    • ,
  • M. Agavriloaie

      Affiliations

    • Pôle d’Anesthésie-Réanimation, Centre Hospitalier Universitaire de Nancy, Nancy, France
    • ,
  • C. Meistelman

      Affiliations

    • Pôle d’Anesthésie-Réanimation, Centre Hospitalier Universitaire de Nancy, Nancy, France
    • ,
  • H. Grégoire

      Affiliations

    • Pôle d’Anesthésie-Réanimation, Centre Hospitalier Universitaire de Nancy, Nancy, France
    • ,
  • P.M. Mertes

      Affiliations

    • Pôle d’Anesthésie-Réanimation, Centre Hospitalier Universitaire de Nancy, Nancy, France
    • ,
  • D. Longrois

      Affiliations

    • Pôle d’Anesthésie-Réanimation, Centre Hospitalier Universitaire de Nancy, Nancy, France

References 

  1. Wood KE, Becker BN, McCartney JG, et al. Care of the potential organ donor. N Engl J Med. 2004;351:2730
  2. Nogueira M, Kavoussi LR, Bhayani SB. Laparoscopic live donor nephrectomy: current status. Br J Urol Int. 2005;95(Suppl 2):59
  3. Merritt WT. Living donor surgery: overview of surgical and anesthesia issues. Anesthesiol Clin North Am. 2004;22:633
  4. Gonzalez-Segura C, Castelao AM, Torras J, et al. A good alternative to reduce the kidney shortage: kidneys from nonheartbeating donors. Transplantation. 1998;65:1465
  5. Recommendations for nonheartbeating organ donation. A position paper by the Ethics Committee, American College of Critical Care Medicine, Society of Critical Care Medicine. Crit Care Med. 2001;29:1826
  6. Mertes PM, Burtin P, Carteaux JP, et al. Brain death and myocardial injury: role of cardiac sympathetic innervation evaluated by in vivo interstitial microdialysis. Transplant Proc. 1994;26:231
  7. Mertes PM, Carteaux JP, Jaboin Y, et al. Estimation of myocardial interstitial norepinephrine release after brain death using cardiac microdialysis. Transplantation. 1994;57:371
  8. Land WG. The role of postischemic reperfusion injury and other nonantigen-dependent inflammatory pathways in transplantation. Transplantation. 2005;79:505
  9. Eskandari F, Webster JI, Sternberg EM. Neural immune pathways and their connection to inflammatory diseases. Arthritis Res Ther. 2003;5:251
  10. Castelli GP, Pognani C, Meisner M, et al. Procalcitonin and C-reactive protein during systemic inflammatory response syndrome, sepsis and organ dysfunction. Crit Care. 2004;8:R234
  11. Meisner M. Pathobiochemistry and clinical use of procalcitonin. Clin Chim Acta. 2002;323:17
  12. Potapov EV, Wagner FD, Loebe M, et al. Elevated donor cardiac troponin T and procalcitonin indicate two independent mechanisms of early graft failure after heart transplantation. Int J Cardiol. 2003;92:163
  13. Wagner FD, Jonitz B, Potapov EV, et al. Procalcitonin, a donor-specific predictor of early graft failure-related mortality after heart transplantation. Circulation. 2001;104(Suppl I):I-192
  14. Cohen S, Tuppin P, Pessione F, et al. Aspects historiques, réglementaires et épidémiologiques de la’mort encéphalique. In:  Boulard G,  Guiot P,  Pottecher T, et al. editor. Prise en charge des sujets en état de mort encéphalique dans l’optique du prélèvement d’organes et de tissus. Paris: Elsevier; 2005;p. 35
  15. Aouifi A, Piriou V, Blanc P, et al. Effect of cardiopulmonary bypass on serum procalcitonin and C-reactive protein concentrations. Br J Anaesth. 1999;83:602
  16. Bell K, Wattie M, Byth K, et al. Procalcitonin: a marker of bacteraemia in SIRS. Anaesth Intens Care. 2003;31:629
  17. Szabo G, Buhmann V, Bahrle S, et al. Brain death impairs coronary endothelial function. Transplantation. 2002;73:1846
  18. Valantine HA. Cardiac allograft vasculopathy: central role of endothelial injury leading to transplant “atheroma.”. Transplantation. 2003;76:891
  19. Pepys MB, Hirschfield GM. C-reactive protein: a critical update. J Clin Invest. 2003;111:1805
  20. Polzin A, Pletz M, Erbes R, et al. Procalcitonin as a diagnostic tool in lower respiratory tract infections and tuberculosis. Eur Respir J. 2003;21:939
  21. Geppert A, Steiner A, Delle-Karth G, et al. Usefulness of procalcitonin for diagnosing complicating sepsis in patients with cardiogenic shock. Intens Care Med. 2003;29:1384
  22. Clec’h C, Fosse JP, Karoubi P, et al. Differential diagnostic value of procalcitonin in surgical and medical patients with septic shock. Crit Care Med. 2006;34:102
  23. Itabashi K, Ito Y, Takahashi T, et al. Protective effects of urinary trypsin inhibitor (UTI) on hepatic microvasculature in hypotensive brain-dead rats. Eur Surg Res. 2002;34:330

PII: S0041-1345(07)00967-0

doi: 10.1016/j.transproceed.2007.02.101

Transplantation Proceedings
Volume 39, Issue 10 , Pages 2970-2974 , December 2007

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