Transplantation Proceedings
Volume 39, Issue 6 , Pages 1771-1772 , July 2007

Protective Effect of an Inhibitor of Interleukin-8 (Meraxin) From Ischemia and Reperfusion Injury in a Rat Model of Kidney Transplantation

  • F. Neri

      Affiliations

    • Department of Surgery and Transplantations, S. Orsola Hospital, University of Bologna, Bologna, Italy
  • ,
  • L. Puviani

      Affiliations

    • Department of Surgery and Transplantations, S. Orsola Hospital, University of Bologna, Bologna, Italy
  • ,
  • M. Tsivian

      Affiliations

    • Department of Surgery and Transplantations, S. Orsola Hospital, University of Bologna, Bologna, Italy
  • ,
  • D. Prezzi

      Affiliations

    • Department of Surgery and Transplantations, S. Orsola Hospital, University of Bologna, Bologna, Italy
  • ,
  • V. Pacilé

      Affiliations

    • Department of Surgery and Transplantations, S. Orsola Hospital, University of Bologna, Bologna, Italy
  • ,
  • G. Cavallari

      Affiliations

    • Department of Surgery and Transplantations, S. Orsola Hospital, University of Bologna, Bologna, Italy
  • ,
  • R. Bertelli

      Affiliations

    • Department of Surgery and Transplantations, S. Orsola Hospital, University of Bologna, Bologna, Italy
  • ,
  • E. Bianchi

      Affiliations

    • Applied Biomedical Research Center (CRBa), S. Orsola Hospital, University of Bologna, Bologna, Italy
  • ,
  • G.L. Piras

      Affiliations

    • Applied Biomedical Research Center (CRBa), S. Orsola Hospital, University of Bologna, Bologna, Italy
  • ,
  • M. Pariali

      Affiliations

    • Applied Biomedical Research Center (CRBa), S. Orsola Hospital, University of Bologna, Bologna, Italy
  • ,
  • B. Cavalieri

      Affiliations

    • Dompè SpA, L’Aquila, Italy.
  • ,
  • R. Bertini

      Affiliations

    • Dompè SpA, L’Aquila, Italy.
  • ,
  • A. Faenza

      Affiliations

    • Department of Surgery and Transplantations, S. Orsola Hospital, University of Bologna, Bologna, Italy
  • ,
  • B. Nardo

      Affiliations

    • Department of Surgery and Transplantations, S. Orsola Hospital, University of Bologna, Bologna, Italy
    • Corresponding Author InformationAddress reprint requests to Bruno Nardo, MD, PhD, Department of Surgery and Transplantation, S. Orsola Hospital, Via Massarenti 9, 40138 Bologna, Italy.

References 

  1. Carmellini M, Stefano RD, Filipponi F, et al. Delayed graft function adversely affects one-year graft survival of cadaveric renal transplants. Transplant Proc. 1996;28:359
  2. De Greef KE, Yesebaert DK, Ghielli M, et al. Neutrophils and acute ischemia-reperfusion injury. J Nephrol. 1998;11:110
  3. Basile DP, Donohoe D, Roethe K, et al. Renal ischemic injury results in permanent damage to peritubular capillaries and influences long-term function. Am J Physiol Renal Physiol. 2001;281:F887
  4. Troncoso P, Ortiz AM, Dominguez J, et al. Use of FTY 720 and ICAM-1 antisense oligonucleotides for attenuating chronic renal damage secondary to ischemia-reperfusion injury. Transplant Proc. 2005;37:4284
  5. Souza D, Bertini R, Vieira A, et al. Repertaxin, a novel inhibitor of rat CXCR2 function, inhbits inflammatory responses that follow intestinal ischemia and reperfusion injury. Br J Pharmacol. 2004;143:132

PII: S0041-1345(07)00597-0

doi: 10.1016/j.transproceed.2007.05.018

Transplantation Proceedings
Volume 39, Issue 6 , Pages 1771-1772 , July 2007