Transplantation Proceedings
Volume 39, Issue 3 , Pages 612-614 , April 2007

Oral Ulcers Produced by Mycophenolate Mofetil in Two Liver Transplant Patients

  • J. Naranjo

      Affiliations

    • Gastroenterology Department, Medicine Service, Clinical Hospital of the University of Chile, Independencia, Santiago, Chile
    • Corresponding Author InformationAddress reprint requests to J. Naranjo, Clinical Hospital of the University of Chile, Santos Dumont 999, Independencia, Santiago, Chile.
    • ,
  • J. Poniachik

      Affiliations

    • Transplant Unit, Clinical Hospital of the University of Chile, Independencia, Santiago, Chile.
    • ,
  • D. Cisco

      Affiliations

    • Transplant Unit, Clinical Hospital of the University of Chile, Independencia, Santiago, Chile.
    • ,
  • J. Contreras

      Affiliations

    • Transplant Unit, Clinical Hospital of the University of Chile, Independencia, Santiago, Chile.
    • ,
  • D. Oksenberg

      Affiliations

    • Transplant Unit, Clinical Hospital of the University of Chile, Independencia, Santiago, Chile.
    • ,
  • J.M. Valera

      Affiliations

    • Transplant Unit, Clinical Hospital of the University of Chile, Independencia, Santiago, Chile.
    • ,
  • J.C. Díaz

      Affiliations

    • Transplant Unit, Clinical Hospital of the University of Chile, Independencia, Santiago, Chile.
    • ,
  • J. Rojas

      Affiliations

    • Transplant Unit, Clinical Hospital of the University of Chile, Independencia, Santiago, Chile.
    • ,
  • G. Cardemil

      Affiliations

    • Transplant Unit, Clinical Hospital of the University of Chile, Independencia, Santiago, Chile.
    • ,
  • S. Mena

      Affiliations

    • Transplant Unit, Clinical Hospital of the University of Chile, Independencia, Santiago, Chile.
    • ,
  • J. Castillo

      Affiliations

    • Transplant Unit, Clinical Hospital of the University of Chile, Independencia, Santiago, Chile.
    • ,
  • G. Rencoret

      Affiliations

    • Transplant Unit, Clinical Hospital of the University of Chile, Independencia, Santiago, Chile.
    • ,
  • J. Godoy

      Affiliations

    • Transplant Unit, Clinical Hospital of the University of Chile, Independencia, Santiago, Chile.
    • ,
  • J. Escobar

      Affiliations

    • Transplant Unit, Clinical Hospital of the University of Chile, Independencia, Santiago, Chile.
    • ,
  • J. Rodríguez

      Affiliations

    • Transplant Unit, Clinical Hospital of the University of Chile, Independencia, Santiago, Chile.
    • ,
  • P. Leyton

      Affiliations

    • Transplant Unit, Clinical Hospital of the University of Chile, Independencia, Santiago, Chile.
    • ,
  • A. Fica

      Affiliations

    • Transplant Unit, Clinical Hospital of the University of Chile, Independencia, Santiago, Chile.
    • ,
  • C. Toledo

      Affiliations

    • Transplant Unit, Clinical Hospital of the University of Chile, Independencia, Santiago, Chile.

References 

  1. Field EA, Allan RB. Review article: oral ulceration—aetiopathogenesis, clinical diagnosis and management in the gastrointestinal clinic. Aliment Pharmacol Ther. 2003;18:949
  2. Garrigue V, Canet S, Dereure O, et al. Oral ulceration in a renal transplant recipient: a mycophenolate mofetil-induced complication?. Transplantation. 2001;72:968
  3. van Gelder T, ter Meulen CG, Hené R, et al. Oral ulcer in kidney transplant recipients treated with sirolimus and mycophenolate mofetil. Transplantation. 2003;75:788
  4. Zucker K, Rosen A, Tsaroucha A, et al. Unexpected augmentation of mycophenolic acid pharmacokinetics in renal transplant patients receiving tacrolimus and mycophenolate mofetil in combination therapy, and analogous in vitro findings. Transpl Immunol. 1997;5:225
  5. Smak Gregoor PHJ, van Gelder T, Hesse CJ, et al. Mycophenolic acid plasma concentration in kidney allograft recipients with or without cyclosporine: a cross-sectional study. Nephrol Dial Transplant. 1999;14:706
  6. Smak Greggor PHJ, De Sévaux RGL, Hené RJ, et al. Effect of cyclosporine on mycophenolic acid trough levels in kidney transplant recipients. Transplantation. 1999;68:1603
  7. Van Gelder T, Klupp J, Barten MJ, et al. Comparison of the effects of tacrolimus and cyclosporine on the pharmacokinetics of mycophenolic acid. Ther Drug Monit. 2001;23:119
  8. Apostolou T, Tsagalis G, Koutroubas G, et al. Mycophenolate mofetil and oral ulcerations. Transplantation. 2004;77:1911
  9. Porter SR, Leao JC. Review article: oral ulcers and its relevance to systemic disorders. Aliment Pharmacol Ther. 2005;21:295

PII: S0041-1345(06)01575-2

doi: 10.1016/j.transproceed.2006.12.028

Transplantation Proceedings
Volume 39, Issue 3 , Pages 612-614 , April 2007

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