Transplantation Proceedings
Volume 38, Issue 9 , Pages 2769-2773 , November 2006

Effects of Ischemia-Reperfusion Injury on Apolipoprotein M Expression in the Liver

  • X. Xu

      Affiliations

    • Research Institute of Organ Transplantation, The Affiliated TongJi Hospital of Huazhong University of Science and Technology, Wuhan, China
    • Comprehensive Laboratory, The Third Affiliated Hospital, Suzhou University, Changzhou, China
    • ,
  • Q. Ye

      Affiliations

    • Research Institute of Organ Transplantation, The Affiliated TongJi Hospital of Huazhong University of Science and Technology, Wuhan, China
    • ,
  • N. Xu

      Affiliations

    • Research Institute of Organ Transplantation, The Affiliated TongJi Hospital of Huazhong University of Science and Technology, Wuhan, China
    • Section of Clinical Chemistry and Pharmacology, Institute of Laboratory Medicine, Lund University, Lund, Sweden.
    • Corresponding Author InformationAddress reprint requests to Dr Ning Xu, Section of Clinical Chemistry and Pharmacology, Institute of Laboratory Medicine, Lund University, S-221 85 Lund, Sweden.
    • ,
  • X. He

      Affiliations

    • Comprehensive Laboratory, The Third Affiliated Hospital, Suzhou University, Changzhou, China
    • ,
  • G. Luo

      Affiliations

    • Comprehensive Laboratory, The Third Affiliated Hospital, Suzhou University, Changzhou, China
    • ,
  • X. Zhang

      Affiliations

    • Comprehensive Laboratory, The Third Affiliated Hospital, Suzhou University, Changzhou, China
    • ,
  • J. Zhu

      Affiliations

    • Comprehensive Laboratory, The Third Affiliated Hospital, Suzhou University, Changzhou, China
    • ,
  • Y. Zhang

      Affiliations

    • Research Institute of Organ Transplantation, The Affiliated TongJi Hospital of Huazhong University of Science and Technology, Wuhan, China
    • ,
  • P. Nilsson-Ehle

      Affiliations

    • Research Institute of Organ Transplantation, The Affiliated TongJi Hospital of Huazhong University of Science and Technology, Wuhan, China
    • Section of Clinical Chemistry and Pharmacology, Institute of Laboratory Medicine, Lund University, Lund, Sweden.

References 

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  2. Wolfrum C, Poy MN, Stoffel M. Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis. Nat Med. 2005;11:418
  3. Zhang XY, Dong X, Zheng L, et al. Specific tissue expression and cellular localization of human apolipoprotein M as determined by in situ hybridization. Acta Histochem. 2003;105:67
  4. Zhang XY, Jiao GQ, Hurtig M, et al. Expression pattern of apolipoprotein M during mouse and human embryogenesis. Acta Histochem. 2004;106:123
  5. Xu N, Hurtig M, Zhang XY, et al. Transforming growth factor-beta down-regulates apolipoprotein M in HepG2 cells. Biochim Biophys Acta. 2004;1683:33
  6. Xu N, Zhang XY, Dong X, et al. Effects of platelet-activating factor, tumor necrosis factor, and interleukin-1alpha on the expression of apolipoprotein M in HepG2 cells. Biochem Biophys Res Commun. 2002;292:944
  7. Xu N, Nilsson-Ehle P, Hurtig M, et al. Both leptin and leptin-receptor are essential for apolipoprotein M expression in vivo. Biochem Biophys Res Commun. 2004;321:916
  8. Xu N, Nilsson-Ehle P, Ahren B. Correlation of apolipoprotein M with leptin and cholesterol in normal and obese subjects. J Nutr Biochem. 2004;15:579
  9. Aldemir M, Bosnak M, Al B, et al. Effects of molsidomine and lexipafant in hepatic ischaemia-reperfusion injury. Injury. 2004;35:232
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  13. Erkasap S, Erkasap N, Koken T, et al. Effect of leptin on renal ischemia-reperfusion damage in rats. J Physiol Biochem. 2004;60:79
  14. Luo G, Hurtig M, Zhang X, et al. Leptin inhibits apolipoprotein M transcription and secretion in human hepatoma cell line, HepG2 cells. Biochim Biophys Acta. 2005;1734:198
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  17. Fallsehr C, Zapletal C, Kremer M, et al. Identification of differentially expressed genes after partial rat liver ischemia/reperfusion by suppression subtractive hybridization. World J Gastroenterol. 2005;11:1303
  18. Higuchi R, Fockler C, Dollinger G, et al. Kinetic PCR analysis: real-time monitoring of DNA amplification reactions. Biotechnology (N Y). 1993;11:1026
  19. Luo G, Zhang X, Nilsson-Ehle P, et al. Apolipoprotein M. Lipids Health Dis. 2004;3:21
  20. Sakai T, Takaya S, Fukuda A, et al. Evaluation of warm ischemia-reperfusion injury using heat shock protein in the rat liver. Transpl Int. 2003;16:88
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  22. Barrett TD, Hennan JK, Marks RM, et al. C-reactive-protein-associated increase in myocardial infarct size after ischemia/reperfusion. J Pharmacol Exp Ther. 2002;303:1007
  23. Thiemermann C, Patel NS, Kvale EO, et al. High density lipoprotein (HDL) reduces renal ischemia/reperfusion injury. J Am Soc Nephrol. 2003;14:1833
  24. Gabay C, Kushner I. Acute-phase proteins and other systemic responses to inflammation. N Engl J Med. 1999;340:448
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 This work was supported by the Nature Science Fund of China (NSFC) (30570752).

PII: S0041-1345(06)01072-4

doi: 10.1016/j.transproceed.2006.08.133

Transplantation Proceedings
Volume 38, Issue 9 , Pages 2769-2773 , November 2006

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