Transplantation Proceedings
Volume 38, Issue 5 , Pages 1243-1246 , June 2006

Molecular Markers in Stored Kidneys Using Perfluorocarbon-based Preservation Solution: Preliminary Results

  • D.G. Maluf

      Affiliations

    • Division of Transplant, Department of Surgery, Virginia Commonwealth University, Richmond, Virginia
    • Corresponding Author InformationAddress reprint requests to Dr Daniel G Maluf, Assistant Professor of Surgery, Transplantation Division, Department of Surgery, Virginia Commonwealth University, WEST HOSPITAL 9TH FL, PO Box: 980057, Richmond, VA 23298-0248.
    • ,
  • V.R. Mas

      Affiliations

    • Division of Transplant, Department of Surgery, Virginia Commonwealth University, Richmond, Virginia
    • Department of Pathology, Virginia Commonwealth University, Richmond, Virginia
    • ,
  • K. Yanek

      Affiliations

    • Division of Transplant, Department of Surgery, Virginia Commonwealth University, Richmond, Virginia
    • ,
  • J.J. Stone

      Affiliations

    • Division of Transplant, Department of Surgery, Virginia Commonwealth University, Richmond, Virginia
    • ,
  • R. Weis

      Affiliations

    • Department of Anesthesiology, Virginia Commonwealth University, Richmond, Virginia
    • VCU Reanimation Engineering Shock Center VCURES, Virginia Commonwealth University, Richmond, Virginia.
    • ,
  • D. Massey

      Affiliations

    • Department of Pathology, Virginia Commonwealth University, Richmond, Virginia
    • ,
  • B. Spiess

      Affiliations

    • Department of Anesthesiology, Virginia Commonwealth University, Richmond, Virginia
    • VCU Reanimation Engineering Shock Center VCURES, Virginia Commonwealth University, Richmond, Virginia.
    • ,
  • M.P. Posner

      Affiliations

    • Division of Transplant, Department of Surgery, Virginia Commonwealth University, Richmond, Virginia
    • ,
  • R.A. Fisher

      Affiliations

    • Division of Transplant, Department of Surgery, Virginia Commonwealth University, Richmond, Virginia

References 

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  2. Ojo AO , Wolfe RA , Held PJ , et al.   Delayed graft function (risk factors and implications for renal allograft survival) . Transplantation . 1997;63:968
  3. Matas AJ , Gillingham KJ , Humar A , et al.   Immunologic and nonimmunologic factors (different risks for cadaver and living donor transplantation) . Transplantation . 2000;69:54
  4. Kacar S , Gurkan A , Varilsuha C , et al.   Marginal donors in kidney transplantation . Ann Transplant . 2004;9:5
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  6. Takada M , Nadeau KC , Shaw GD , et al.   The cytokine-adhesion molecule cascade in ischemia/reperfusion injury of the rat kidney (inhibition by a soluble P-selectin ligand) . J Clin Invest . 1997;99:2682
  7. Herskowitz A , Choi S , Ansari AA , et al.   Cytokine mRNA expression in postischemic/reperfused myocardium . Am J Pathol . 1995;146:419
  8. Otterbein L , Choi AMK . Heme oxygenase (colors of defense against cellular stress) . Am J Physiol Lung Cell Mol Physiol . 2000;279:L1029
  9. Agarwal A , Nick HS . Renal response to tissue injury (lessons from heme oxygenase-1 gene ablation and expression) . J Am Soc Nephrol . 2000;11:965
  10. Maines MD . The heme oxygenase system (a regulator of second messenger gases) . Annu Rev Pharmacol Toxicol . 1997;37:517
  11. Gage FA , Vodovotz Y . Normalization of nitric oxide flux improves physiological parameters of porcine kidneys maintained on pulsatile perfusion . Nitric Oxide . 2003;9:141
  12. Shorr RG . IBC’s 5th annual conference on blood substitutes . Expert Opin Investig Drugs . 1998;7:283
  13. Matsumoto S , Kandaswamy R , Sutherland DE , et al.   Clinical application of the two-layer (University of Wisconsin solution/perfluorochemical plus O2) method of pancreas preservation before transplantation . Transplantation . 2000;70:771
  14. Iwanaga Y , Suzuki Y , Okada Y , et al.   Ultrastructural analyses of pancreatic grafts preserved by the two-layer cold-storage method and by simple cold storage in University of Wisconsin solution . Transpl Int . 2002;15:425
  15. Keitaro K , Yasuhiro F , Yasuyuki S , et al.   Protection against ischemia/reperfusion injury by the cavitary two-layer method in canine small intestinal transplantation with reduction of reactive oxygen species . Surgery . 2004;135:642
  16. DeRoover A , Krafft MP , Deby-Dupont G , et al.   Seventy-two hours hypothermic intestinal preservation study using a new perfluorocarbon emulsion . Artif Cells Blood Substit Immobil Biotechnol . 2001;29:225
  17. Cheng PY , Chen JJ , Yen MH . The expression of heme oxygenase-1 and inducible nitric oxide synthase in aorta during the development of hypertension in spontaneously hypertensive rats . Am J Hypertens . 2004;17:1127
  18. Willis D , Moore AR , Frederick R , et al.   Heme oxygenase (a novel target for the modulation of the inflammatory response) . Nat Med . 1996;2:87
  19. Klahr S , Morrissey J . Renal disease (the two faces of nitric oxide) . Lab Invest . 1995;72:1

PII: S0041-1345(06)00199-0

doi: 10.1016/j.transproceed.2006.02.109

Transplantation Proceedings
Volume 38, Issue 5 , Pages 1243-1246 , June 2006

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