Transplantation Proceedings
Volume 36, Issue 10 , Pages 3212-3219 , December 2004

Race, education, and knowledge of bone marrow registry: Indicators of willingness to donate bone marrow among African Americans and Caucasians

  • A.A. Onitilo

      Affiliations

    • Division of Hematology/Oncology (A.A.O., L.A.), Department of Internal Medicine; Department of Biostatistics, Bioinformatics and Epidemiology (A.A.O., Y.L., E.O., L.A., B.T.); Division of General Internal Medicine (A.A.O., E.O.), Department of Internal Medicine; The Writing Center for Academic Excellence (J.A.), Medical University of South Carolina, Charleston, South Carolina
    • Marshfield Clinic (A.A.O.), Wausau Center, Wausau, Wisconsin
    • Corresponding Author InformationAddress reprint requests to Dr A.A. Onitilo, Department of Medicine, Division of Hematology/Oncology, Medical University of South Carolina, 96 Jonathan Lucas St, CSB903, PO Box 250632, Charleston, SC 29414
  • ,
  • Y.H. Lin

      Affiliations

    • Division of Hematology/Oncology (A.A.O., L.A.), Department of Internal Medicine; Department of Biostatistics, Bioinformatics and Epidemiology (A.A.O., Y.L., E.O., L.A., B.T.); Division of General Internal Medicine (A.A.O., E.O.), Department of Internal Medicine; The Writing Center for Academic Excellence (J.A.), Medical University of South Carolina, Charleston, South Carolina
  • ,
  • E.C. Okonofua

      Affiliations

    • Division of Hematology/Oncology (A.A.O., L.A.), Department of Internal Medicine; Department of Biostatistics, Bioinformatics and Epidemiology (A.A.O., Y.L., E.O., L.A., B.T.); Division of General Internal Medicine (A.A.O., E.O.), Department of Internal Medicine; The Writing Center for Academic Excellence (J.A.), Medical University of South Carolina, Charleston, South Carolina
  • ,
  • L.B. Afrin

      Affiliations

    • Division of Hematology/Oncology (A.A.O., L.A.), Department of Internal Medicine; Department of Biostatistics, Bioinformatics and Epidemiology (A.A.O., Y.L., E.O., L.A., B.T.); Division of General Internal Medicine (A.A.O., E.O.), Department of Internal Medicine; The Writing Center for Academic Excellence (J.A.), Medical University of South Carolina, Charleston, South Carolina
  • ,
  • J. Ariail

      Affiliations

    • Division of Hematology/Oncology (A.A.O., L.A.), Department of Internal Medicine; Department of Biostatistics, Bioinformatics and Epidemiology (A.A.O., Y.L., E.O., L.A., B.T.); Division of General Internal Medicine (A.A.O., E.O.), Department of Internal Medicine; The Writing Center for Academic Excellence (J.A.), Medical University of South Carolina, Charleston, South Carolina
  • ,
  • B.C. Tilley

References 

  1. Armitage JO . Bone marrow transplantation . N Engl J Med . 1994;330:827
  2. Thomas ED . Karnofsky Memorial Lecture. Marrow transplantation for malignant diseases . J Clin Oncol . 1983;1:517
  3. Thomas ED . Marrow transplantation for nonmalignant disorders . N Engl J Med . 1985;312:46
  4. Thomas ED . Marrow transplantation for malignant disease . Am J Med Sci . 1987;294:75
  5. McCullough J , Rogers G , Dahl R , et al.  Development and operation of a program to obtain volunteer bone marrow donors unrelated to the patient . Transfusion . 1986;26:315
  6. Yancey AK , Coppo P , Kawanishi Y . Progress in availability of donors of color: the National Marrow Donor Program . Transplant Proc . 1997;29:3760
  7. Buckley RH . 27. Transplantation immunology: organ and bone marrow . J Allergy Clin Immunol . 2003;111:S733
  8. Cecka JM . Results of more than 1000 recent living-unrelated donor transplants in the United States . Transplant Proc . 1999;31:234
  9. National Marrow Donor Program: General Facts and Figures . http://www.marrow.org/NMDP/general_facts_figures.html 2003; Accessed December 14
  10. Appelbaum FR, Keal HJ: Prospective cooperative study of bone marrow transplantation versus continued chemotherapy for adult nonlymphocytic leukemia: a Southwest Oncology Group Study [abstract]. Blood 68: 1986
  11. Beatty PG , Mori M , Milford E . Impact of racial genetic polymorphism on the probability of finding an HLA-matched donor . Transplantation . 1995;60:778
  12. Karanes C , Confer D , Walker T , et al.  Unrelated donor stem cell transplantation: the role of the National Marrow Donor Program . Oncology (Huntingt) . 2003;17:1036
  13. Mitchell JM , Meehan KR , Kong J , et al.  Access to bone marrow transplantation for leukemia and lymphoma: the role of sociodemographic factors . J Clin Oncol . 1997;15:2644
  14. Jemal A , Murray T , Samuels A , et al.  Cancer statistics, 2003 . CA Cancer J Clin . 2003;53:5
  15. Kollman C , Weis T , Switzer GE , et al.  Non-HLA barriers to unrelated donor stem cell transplantation . Bone Marrow Transplant . 2001;27:581
  16. Ellis JM , Mack SJ , Leke RF , et al.  Diversity is demonstrated in class I HLA-A and HLA-B alleles in Cameroon, Africa: description of HLA-A*03012, *2612, *3006 and HLA-B*1403, *4016, *4703 . Tissue Antigens . 2000;56:291
  17. Ellis JM , Henson V , Slack R , et al.  Frequencies of HLA-A2 alleles in five U.S. population groups. Predominance of A*02011 and identification of HLA-A*0231 . Hum Immunol . 2000;61:334
  18. Tang TF , Huang AY , Pappas A , et al.  Relative frequencies of DRB1*11 alleles and their DRB3 associations in live major population groups in a United States bone marrow registry . Hum Immunol . 2000;61:820
  19. Ayanian JZ , Cleary PD , Weissman JS , et al.  The effect of patients' preferences on racial differences in access to renal transplantation . N Engl J Med . 1999;341:1661
  20. Freimuth VS , Quinn SC , Thomas SB , et al.  African Americans' views on research and the Tuskegee Syphilis Study . Soc Sci Med . 2001;52:797
  21. Switzer GE , Myaskovsky L , Goycoolea JM , et al.  Factors associated with ambivalence about bone marrow donation among newly recruited unrelated potential donors . Transplantation . 2003;75:1517
  22. Davidson MN , Devney P . Attitudinal barriers to organ donation among black Americans . Transplant Proc . 1991;23:2531
  23. Laver JH , Hulsey TC , Jones JP , et al.  Assessment of barriers to bone marrow donation by unrelated African-American potential donors . Biol Blood Marrow Transplant . 2001;7:45
  24. South CarolinaQuickFacts from the U.S. Census Bureau . http://www.quickfacts.census.gov/qfd/states/45000.html Accessed August 2, 2004
  25. Minniefield WJ , Muti P . Organ donation survey results of a Buffalo, New York, African-American community . J Natl Med Assoc . 2002;94:979
  26. Sanner MA . Giving and taking—to whom and from whom? People's attitudes toward transplantation of organs and tissue from different sources . Clin Transplant . 1998;12:530
  27. Briggs NC , Piliavin JA , Lorentzen D , et al.  On willingness to be a bone marrow donor . Transfusion . 1986;26:324
  28. Brown DR , Topcu M . Willingness to participate in clinical treatment research among older African Americans and Whites . Gerontologist . 2003;43:62
  29. Minniefield WJ , Yang J , Muti P . Differences in attitudes toward organ donation among African Americans and whites in the United States. J Natl Med Assoc . 2001;93:372
  30. American Comunity Survey Change Profile 2001–2002 United States Census Bureau . http://www.census.gov/acs/www/Products/Profiles/Chg/2002/0102/Tabular/010/1000US1.htm Accessed December 14, 2003
  31. Schwartz SH . Elicitation of moral obligation and self-sacrificing behavior: an experimental study of volunteering to be a bone marrow donor . J Pers Soc Psychol . 1970;15:283
  32. Callendar CO , Hall LE , Yeager CL , et al.  Organ donation and blacks (A critical frontier) . N Engl J Med . 1991;325:442
  33. Venkat A , Hoekstra J , Lindsell C , et al.  The impact of race on the acute management of chest pain . Acad Emerg Med . 2003;10:1199
  34. Anderson KO , Mendoza TR , Valero V , et al.  Minority cancer patients and their providers: pain management attitudes and practice . Cancer . 2000;88:1929
  35. Green CR , Anderson KO , Baker TA , et al.  The unequal burden of pain: confronting racial and ethnic disparities in pain . Pain Med . 2003;4:277
  36. Peters TG , Kittur DS , McGaw LJ , et al.  Organ donors and nondonors (An American dilemma) . Arch Intern Med . 1996;156:2419
  37. Freimuth VS , Quinn SC , Thomas SB , et al.  African Americans' views on research and the Tuskegee Syphilis Study . Soc Sci Med . 2001;52:797
  38. Switzer GE , Dew MA , Stukas AA , et al.  Factors associated with attrition from a national bone marrow registry . Bone Marrow Transplant . 1999;24:313
  39. Klock SC , Stout JE , Davidson M . Psychological characteristics and factors related to willingness to donate again among anonymous oocyte donors . Fertil Steril . 2003;79:1312
  40. Switzer GE , Dew MA , Butterworth VA , et al.  Understanding donors' motivations: a study of unrelated bone marrow donors . Soc Sci Med . 1997;45:137
  41. Switzer GE , Goycoolea JM , Dew MA , et al.  Donating stimulated peripheral blood stem cells vs bone marrow: do donors experience the procedures differently? . Bone Marrow Transplant . 2001;27:917
  42. Ballen KK , Hicks J , Dharan B , et al.  Racial and ethnic composition of volunteer cord blood donors: comparison with volunteer unrelated marrow donors . Transfusion . 2002;42:1279

PII: S0041-1345(04)01185-6

doi: 10.1016/j.transproceed.2004.10.019

Transplantation Proceedings
Volume 36, Issue 10 , Pages 3212-3219 , December 2004