Transplantation Proceedings
Volume 36, Issue 6 , Pages 1728-1731 , July 2004

Humoral sensitization against rejected grafts: Specific antibodies to graft immunogenic amino acid triplets

  • A. Iniotaki-Theodoraki

      Affiliations

    • National Tissue Typing Center, General Hospital of Athens, Athens, Greece (A.I.-T., E.K., M.A., C.S.-G.)
    • Corresponding Author InformationAddress reprint requests to Dr Aliki Iniotaki-Theodoraki, National Tissue Typing Center, General Hospital of Athens, 34 Davaki Street, 174 55, Alimos, Athens, Greece
  • ,
  • E. Kalogeropoulou

      Affiliations

    • National Tissue Typing Center, General Hospital of Athens, Athens, Greece (A.I.-T., E.K., M.A., C.S.-G.)
  • ,
  • M. Apostolaki

      Affiliations

    • National Tissue Typing Center, General Hospital of Athens, Athens, Greece (A.I.-T., E.K., M.A., C.S.-G.)
  • ,
  • I.N. Doxiadis

      Affiliations

    • Immunohaematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands (I.N.D.)
  • ,
  • C. Stavropoulos-Giokas

      Affiliations

    • National Tissue Typing Center, General Hospital of Athens, Athens, Greece (A.I.-T., E.K., M.A., C.S.-G.)

References 

  1. El-Awar N , Terasaki PI , Lazda V , et al.  Almost all patients who are waiting for a regraft of a kidney transplant have anti-HLA antibodies . Transplant Proc . 2002;34:2531
  2. Papassavas A , Iniotaki-Theodoraki A , Boletis J , et al.  Giokas epitope analysis of HLA class I donor specific antibodies in sensitized renal transplant recipients . Transplantation . 2000;70:323
  3. Duquesnoy R . HLAMatchmaker: A molecularly based algorithm for histocompatibility determination. I. Description of the algorithm . Hum Immunol . 2002;63:339
  4. Duquesnoy R , Marrari M . A molecularly based algorithm for histocompatibility determination. Verification of the algorithm and determination of the relative immunogenicity of amino acid triplets–defined epitopes . Hum Immunol . 2002;63:353
  5. Wood K: Immunological Pathways of Rejection in Sensitized Recipients. Retransplantation. Dordrecht: Kluwer; 1997, p 91
  6. Suciu-Foca N , Harris P , Cortesini R . Intramolecular and intermolecular spreading during the course of organ allograft rejection . Immunol Rev . 1998;164:241
  7. Scornic J , Clapp W , Patton P , Van der Werf W , et al.  Outcome of kidney transplants in patients known to be flow cytometry crossmatch positive . Transplantation . 2001;71:1098
  8. Sercarz EE , Lehmann PV , Ametani A , et al.  Dominance and crypticity of T cell antigenic determinants . Annu Rev Immunol . 1993;11:729
  9. Terasaki P . Humoral theory of transplantation . Am J Transplant . 2003;3:665

 

PII: S0041-1345(04)00670-0

doi: 10.1016/j.transproceed.2004.06.005

Transplantation Proceedings
Volume 36, Issue 6 , Pages 1728-1731 , July 2004