Transplantation Proceedings
Volume 36, Issue 5 , Pages 1613-1614 , June 2004

Effect of human somatotropin hormone on cultured rat islets

  • A.O Gürol

      Affiliations

    • Istanbul University, Institute for Experimental Medical Research, Department of Immunology (A.O.G., G.Y., A.Ö.K., B.K., E.A., G.D., M.T.Y.), Istanbul, Turkey
    • Istanbul Faculty of Medicine, Internal Medicine Department (S.S., M.T.Y.), Diabetes Division, Istanbul, Turkey
    • Corresponding Author InformationAddress reprint requests to Dr Ali Osman Gürol, Istanbul University, Institute for Experimental Medical Research, Department of Immunology, Çapa, 34280, Istanbul, Turkey
    • ,
  • G Yıllar

      Affiliations

    • Istanbul University, Institute for Experimental Medical Research, Department of Immunology (A.O.G., G.Y., A.Ö.K., B.K., E.A., G.D., M.T.Y.), Istanbul, Turkey
    • Istanbul Faculty of Medicine, Internal Medicine Department (S.S., M.T.Y.), Diabetes Division, Istanbul, Turkey
    • ,
  • A.Ö Kurşun

      Affiliations

    • Istanbul University, Institute for Experimental Medical Research, Department of Immunology (A.O.G., G.Y., A.Ö.K., B.K., E.A., G.D., M.T.Y.), Istanbul, Turkey
    • Istanbul Faculty of Medicine, Internal Medicine Department (S.S., M.T.Y.), Diabetes Division, Istanbul, Turkey
    • ,
  • B Kıran

      Affiliations

    • Istanbul University, Institute for Experimental Medical Research, Department of Immunology (A.O.G., G.Y., A.Ö.K., B.K., E.A., G.D., M.T.Y.), Istanbul, Turkey
    • Istanbul Faculty of Medicine, Internal Medicine Department (S.S., M.T.Y.), Diabetes Division, Istanbul, Turkey
    • ,
  • E Aktaş

      Affiliations

    • Istanbul University, Institute for Experimental Medical Research, Department of Immunology (A.O.G., G.Y., A.Ö.K., B.K., E.A., G.D., M.T.Y.), Istanbul, Turkey
    • Istanbul Faculty of Medicine, Internal Medicine Department (S.S., M.T.Y.), Diabetes Division, Istanbul, Turkey
    • ,
  • S Salman

      Affiliations

    • Istanbul University, Institute for Experimental Medical Research, Department of Immunology (A.O.G., G.Y., A.Ö.K., B.K., E.A., G.D., M.T.Y.), Istanbul, Turkey
    • Istanbul Faculty of Medicine, Internal Medicine Department (S.S., M.T.Y.), Diabetes Division, Istanbul, Turkey
    • ,
  • G Deniz

      Affiliations

    • Istanbul University, Institute for Experimental Medical Research, Department of Immunology (A.O.G., G.Y., A.Ö.K., B.K., E.A., G.D., M.T.Y.), Istanbul, Turkey
    • Istanbul Faculty of Medicine, Internal Medicine Department (S.S., M.T.Y.), Diabetes Division, Istanbul, Turkey
    • ,
  • M.T Yılmaz

      Affiliations

    • Istanbul University, Institute for Experimental Medical Research, Department of Immunology (A.O.G., G.Y., A.Ö.K., B.K., E.A., G.D., M.T.Y.), Istanbul, Turkey
    • Istanbul Faculty of Medicine, Internal Medicine Department (S.S., M.T.Y.), Diabetes Division, Istanbul, Turkey

References 

  1. Rabinovitch A, Quigley C, Rechler MM. Growth hormone stimulates islet β-cell replication in neonatal rat pancreatic monolayer cultures. Diabetes. 1983;32:307
  2. Sjoholm A, Hellrstrom C. TGF-β stimulates insulin secretion and blocks mitogenic response of pancreatic β-cells to glucose. Am J Physiol. 1991;260:C1046
  3. Nielsen JH, Svensson C, Galsgaard ED, et al.  β-cell proliferation and growth factors. J Mol Med. 1999;77:62
  4. Djordjević PB, Lalić NM, Jotić A, et al.  Requirements for the beneficial effect of long-term incubation with growth hormone on insulin secretion from isolated human fetal islets. Transplant Proc. 1998;30:602
  5. Lalić NM, Djordjević PB, Jotić A, et al.  Determinants of the beneficial effect of long-term incubation with growth hormone on insulin secretion capacity from human fetal islets. Horm Metab Res. 1998;30:A15

PII: S0041-1345(04)00503-2

doi: 10.1016/j.transproceed.2004.04.071

Transplantation Proceedings
Volume 36, Issue 5 , Pages 1613-1614 , June 2004

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