Transplantation Proceedings
Volume 36, Issue 3 , Pages 603-604 , April 2004

Islet transplantation in type 1 diabetic patients

  • F. Bertuzzi

      Affiliations

    • Medical Surgical Department, Medicine Department, S Raffaele Scientific Institute, Milan, Italy
    • Corresponding Author InformationAddress reprint requests to Federico Bertuzzi, S Raffaele Scientific Institute, Via Olgettina 60, 201321 Milan, Italy
  • ,
  • A. Secchi

      Affiliations

    • Medical Surgical Department, Medicine Department, S Raffaele Scientific Institute, Milan, Italy
  • ,
  • V.Di Carlo

      Affiliations

    • Medical Surgical Department, Medicine Department, S Raffaele Scientific Institute, Milan, Italy

References 

  1. Brendel MD, Hering BJ, Schultz AO, et al: International Islet Transplant Registry. Newsletter 8:9, 2000
  2. Bertuzzi F, Grohovaz F, Maffi P, et al.  Successful transplantation of human islets in recipients bearing a kidney graft. Diabetologia. 2002;45:77
  3. Shapiro AMJ, Lakey JRT, Ryan EA, et al.  Islet transplantation in seven patients with type 1 diabetes mellitus using a glucorticoid-free immunosuppressive regimen. N Engl J Med. 2000;343:230
  4. Piemonti L, Leone BE, Nano R, et al.  Human pancreatic islets produce and secrete MCP-1 (relevance in human islet transplantation). Diabetes. 2002;51:55
  5. Luzi L, Perseghin G, Brendel MD, et al.  Metabolic effects of restoring partial b-cell function after islet allotransplantation in type 1 diabetic patients. Diabetes. 2001;50:277
  6. Fiorina P, Folli F, Bertuzzi F, et al.  Long term beneficial effect of islet transplantation on diabetic complications in type 1 diabetic kidney transplanted patients. A study of 34 consecutive cases. Diabetes. 2002;51(Suppl 2):A34
  7. Bosi E, Braghi S, Maffi P, et al.  Autoantibody response to islet transplantation in type 1 diabetes. Diabetes. 2001;50:2464
  8. Davalli AM, Maffi P, Socci C, et al.  Insights from a successful case of intrahepatic islet transplantation into a type 1 diabetic patient. J Clin Endocr Metab. 2000;85:3847
  9. Brandhorst H, Brandhorst D, Hesse F, et al.  Successful human islet isolation utilizing recombinant collagenase. Diabetes. 2003;52:1143

 We gratefully acknowledge the financial support of JDF (I 2000-780) and JDF Innovative Grant (5-2001 + 172).

PII: S0041-1345(04)00190-3

doi: 10.1016/j.transproceed.2004.02.046

Transplantation Proceedings
Volume 36, Issue 3 , Pages 603-604 , April 2004