Transplantation Proceedings
Volume 35, Issue 3, Supplement , Pages S37-S51 , May 2003

Two-year results of multicenter phase III trials on the effect of the addition of sirolimus to Cyclosporine-based immunosuppressive regimens in renal transplantation

  • B.D Kahan

      Affiliations

    • University of Texas Medical School at Houston, Department of Surgery, Division of Immunology and Organ Transplantation, Houston, TX, USA
    • Corresponding Author InformationAddress reprint requests to Dr B.D. Kahan, University of Texas Medical School at Houston, Department of Surgery, Division of Immunology and Organ Transplantation, 6431 Fannin, Suite 6.240, Houston, TX 77030, USA.

References 

  1. Kahan BD  Rapamune U.S. Study Group . Lancet. 2000;356:194
  2. MacDonald AS  Rapamune Global Study Group . Transplantation. 2001;71:271
  3. Kahan BD. N Engl J Med. 1989;321:1725
  4. Napoli KL, Wang ME, Stepkowski SM, et al.  Ther Drug Monit. 1998;20:123
  5. Kaplan B, Meier-Kriesche HU, Napoli KL, et al.  Clin Pharmacol Ther. 1998;63:48
  6. Kelly PA, Wang H, Napoli KL, et al.  Eur J Drug Metab Pharmacokinet. 1999;24:321
  7. Lo A, Burckart GJ. J Clin Pharmacol. 1999;39:995
  8. Kahan BD, Kramer WG. Clin Pharmacol Ther. 2001;70:74
  9. Mathew T. Transplantation. 1998;65:1450
  10. Ojo AO, Port FK, Held PJ, et al.  Kidney Int. 1995;48:1592
  11. Solez K, Axelsen RA, Benediktsson H, et al.  Kidney Int. 1993;44:411
  12. Nankivell BJ, Gruenewald SM, Allen RD, et al.  Transplantation. 1995;59:1683
  13. Fleiss JL. In: Statistical methods for rates and proportions. New York: Wiley; 1981;p. 44
  14. Kahan BD, Julian BA, Pescovitz MD  Rapamune Study Group . Transplantation. 1999;68:1526
  15. Begg C, Cho M, Eastwood S, et al.  JAMA. 1996;276:637
  16. Kahan BD, Welsh M, Urbauer DL, et al.  J Am Soc Nephrol. 2000;11:1122
  17. Lindholm A, Kahan BD. Clin Pharmacol Ther. 1993;54:205
  18. Podder H, Podbielski J, Hussein I, et al.  Transpl Int. 2001;14:135
  19. Podder H, Stepkowski SM, Napoli KL, et al.  J Am Soc Nephrol. 2001;12:1059
  20. Kahan BD, Napoli KL, Kelly PA, et al.  Clin Transplant. 2000;14:97

☆ Supported in part by Wyeth Research.

PII: S0041-1345(03)00353-1

doi: 10.1016/S0041-1345(03)00353-1

Transplantation Proceedings
Volume 35, Issue 3, Supplement , Pages S37-S51 , May 2003

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