Transplantation Proceedings
Volume 34, Issue 5 , Pages 1392-1393 , August 2002

Sirolimus inhibits growth of human hepatoma cells in contrast to tacrolimus which promotes cell growth

  • G Schumacher

      Affiliations

    • Department of General-, Visceral-, and Transplantation Surgery (G.S., M.O., J.M.L., S.J., A.R.M., R.N., M.B., D.J., P.N.), Berlin, Germany
    • Corresponding Author InformationAddress reprint requests to Dr Guido Schumacher, Department of General-, Visceral-, and Transplantation Surgery, Charité Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany.
    • ,
  • M Oidtmann

      Affiliations

    • Department of General-, Visceral-, and Transplantation Surgery (G.S., M.O., J.M.L., S.J., A.R.M., R.N., M.B., D.J., P.N.), Berlin, Germany
    • ,
  • S Rosewicz

      Affiliations

    • Gastroenterology (S.R.),, Berlin, Germany
    • ,
  • J.M Langrehr

      Affiliations

    • Department of General-, Visceral-, and Transplantation Surgery (G.S., M.O., J.M.L., S.J., A.R.M., R.N., M.B., D.J., P.N.), Berlin, Germany
    • ,
  • S Jonas

      Affiliations

    • Department of General-, Visceral-, and Transplantation Surgery (G.S., M.O., J.M.L., S.J., A.R.M., R.N., M.B., D.J., P.N.), Berlin, Germany
    • ,
  • A.R Mueller

      Affiliations

    • Department of General-, Visceral-, and Transplantation Surgery (G.S., M.O., J.M.L., S.J., A.R.M., R.N., M.B., D.J., P.N.), Berlin, Germany
    • ,
  • A Rueggeberg

      Affiliations

    • Anesthesiology (A.R., H.G.); Charité Campus Virchow Klinikum, Humboldt University, Berlin, Germany
    • ,
  • R Neuhaus

      Affiliations

    • Department of General-, Visceral-, and Transplantation Surgery (G.S., M.O., J.M.L., S.J., A.R.M., R.N., M.B., D.J., P.N.), Berlin, Germany
    • ,
  • M Bahra

      Affiliations

    • Department of General-, Visceral-, and Transplantation Surgery (G.S., M.O., J.M.L., S.J., A.R.M., R.N., M.B., D.J., P.N.), Berlin, Germany
    • ,
  • D Jacob

      Affiliations

    • Department of General-, Visceral-, and Transplantation Surgery (G.S., M.O., J.M.L., S.J., A.R.M., R.N., M.B., D.J., P.N.), Berlin, Germany
    • ,
  • H Gerlach

      Affiliations

    • Anesthesiology (A.R., H.G.); Charité Campus Virchow Klinikum, Humboldt University, Berlin, Germany
    • ,
  • P Neuhaus

      Affiliations

    • Department of General-, Visceral-, and Transplantation Surgery (G.S., M.O., J.M.L., S.J., A.R.M., R.N., M.B., D.J., P.N.), Berlin, Germany

References 

  1. Neuhaus P, Klupp J, Langrehr JM. Liver Transpl. 2001;7:473
  2. Hosoi H, Dilling MB, Shikata T, et al.  Cancer Res. 1999;59:886
  3. Ogawa T, Tokuda M, Tomizawa K, et al.  Biochem Biophys Res Commun. 1998;249:226
  4. Price DJ, Grove JR, Calvo V, et al.  Science. 1992;257:973
  5. Seufferlein T, Rozengurt E. Cancer Res. 1996;56:3895
  6. Muthukkumar S, Ramesh TM, Bondada S. Transplantation. 1995;60:264
  7. Baksh S, DeCaprio JA, Burakoff SJ. Oncogene. 2000;19:2820
  8. McAlister VC, Peltekian KM, Malatjalian DA, et al.  Liver Transpl. 2001;7:701
  9. Metcalfe SM, Canman CE, Milner J, et al.  Oncogene. 1997;15:1635

PII: S0041-1345(02)02899-3

Transplantation Proceedings
Volume 34, Issue 5 , Pages 1392-1393 , August 2002

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