Transplantation Proceedings
Volume 33, Issue 3 , Pages 2094-2095 , May 2001

Leflunomide and its analogue X920715 synergize with cyclosporin A in preventing early graft failure and delaying graft rejection of xenogeneic islets in nonobese diabetic mice

  • C Gysemans

      Affiliations

    • Department of Experimental Medicine and Endocrinology (LEGENDO) (C.G., J.L., R.B., C.M.), Catholic University of Leuven, Campus Gaithuisberg, Leuven, Belgium
    • ,
  • M Waer

      Affiliations

    • Laboratory for Experimental Transplantation (M.W.), Catholic University of Leuven, Campus Gasthuisberg, Leuven, Belgium
    • ,
  • J Laureys

      Affiliations

    • Department of Experimental Medicine and Endocrinology (LEGENDO) (C.G., J.L., R.B., C.M.), Catholic University of Leuven, Campus Gaithuisberg, Leuven, Belgium
    • ,
  • R Bouillon

      Affiliations

    • Department of Experimental Medicine and Endocrinology (LEGENDO) (C.G., J.L., R.B., C.M.), Catholic University of Leuven, Campus Gaithuisberg, Leuven, Belgium
    • ,
  • C Mathieu

      Affiliations

    • Department of Experimental Medicine and Endocrinology (LEGENDO) (C.G., J.L., R.B., C.M.), Catholic University of Leuven, Campus Gaithuisberg, Leuven, Belgium
    • Corresponding Author InformationAddress reprint requests to Prof Dr Chantal Mathieu, Campus Gasthuisberg, LEGENDO, Herestraat 49, B-3000 Leuven, Belgium

References 

  1. Kaufman DB, Platt JL, Rabe FL, et al.  J Exp Med. 1990;172:291
  2. Hyon SH, Tracey KJ, Kaufman DB. Transplant Proc. 1998;30:409
  3. Greene S, Watanabe K, Braatz-Trulson J, et al.  Biochem Pharmacol. 1995;50:861

☆ This work was supported by grants of the Flemish Research Foundation [Fonds voor Wetenschappelijk Onderzoek (FWO) Levenslijn 7.0013.96] and a postdoctoral fellowship for C. Mathieu.

PII: S0041-1345(01)01961-3

Transplantation Proceedings
Volume 33, Issue 3 , Pages 2094-2095 , May 2001

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